Pulsed Gradient Stimulated Echo (PGStE) NMR shows spatial dependence of fluid diffusion in Human Stage IV OA Cartilage

摘要

PurposeHuman Osteoarthritic (OA) articular cartilage was investigated with spatially resolved pulsed gradient stimulated echo (PGStE) nuclear magnetic resonance (NMR) using strong gradients. In this study, the diffusivity of fluid and biopolymer was characterized as a function of depth within human OA cartilage cores.