T68. DIFFERENT INFLUENCES OF INTELLECTUAL FUNCTIONING AND COGNITIVE PERFORMANCE TO FUNCTIONAL OUTCOMES IN SCHIZOPHRENIA AND HEALTHY CONTROLS

摘要

BackgroundIndividuals with schizophrenia (SZ) have marked functional impairments in wide range of domains, such as employment, independent living and interpersonal relationships. Several clinical, cognitive and psychological factors have been shown to predict functional outcomes. However, current pharmacological and psychosocial treatments have failed to rehabilitate patients, which indicates that the mechanisms of functional outcomes are not completely clear. Therefore, we aimed to better understand the relationship between intellectual and cognitive performance to functional outcome of subjects with SZ compared to unaffected individuals. Considering the neurodevelopmental course of SZ, our hypothesis was that premorbid crystallized IQ would interact with cognition to influence functionality.