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Lumbar bone erosion with anterior dural ectasia in ankylosingspondylitis: a case report

机译:腰椎骨侵蚀伴前硬脑膜扩张脊柱炎:一例报告

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摘要

Bony erosion and dural ectasia rarely occur in the posterior part of the vertebral body in ankylosing spondylitis (AS). Because of the compression of nerve tissue that adheres to the inflamed dura mater, a range of neurologic symptoms may develop. Few studies have investigated therapies for this condition, and surgical intervention might alleviate the neurologic dysfunction. Here, we report an uncommon case of lumbar spinal cord herniation secondary to anterior dural ectasia in a patient with AS. The patient had a 31-year history of AS and presented with progressive numbness and weakness of his left leg that had lasted for nearly 1 month. Magnetic resonance imaging (MRI) revealed a dural defect in the posterior aspect of the L1 and L2 vertebral bodies, with displacement of the nerve tissue adjacent to the lytic lesion. The patient declined surgery and was prescribed oral meloxicam. The neurological symptoms of the left leg remained stable during 2 years of follow-up. The dural enhancement on MRI resolved, although the erosion-like lesion in the vertebral bodies persisted. This unusual case supports the central role of inflammation in anterior dural ectasia of patients with AS. Anti-inflammatory treatment may be an alternative therapy for patients who decline surgery.
机译:在强直性脊柱炎(AS)中,椎体后部很少发生骨侵蚀和硬脑膜扩张。由于粘附在发炎硬脑膜上的神经组织受压,可能会出现一系列神经系统症状。很少有研究针对这种情况的疗法进行研究,并且手术干预可能会减轻神经功能障碍。在这里,我们报道了AS患者中继发于硬脑膜前扩张的腰椎脊髓突出的罕见病例。该患者有AS病史31年,左腿进行性麻木和无力,持续了近1个月。磁共振成像(MRI)显示L1和L2椎体后方存在硬脑膜缺损,邻近溶解性病变的神经组织移位。该患者拒绝手术,并被要求口服美洛昔康。在随访的2年中,左腿的神经系统症状保持稳定。 MRI的硬脑膜增强得以解决,尽管椎体中仍出现糜烂样病变。这种不寻常的情况支持了炎症在AS患者的硬脑膜前扩张中的重要作用。对于拒绝手术的患者,抗炎治疗可能是另一种治疗方法。

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