PNRC is a unique nuclear receptor coactivator that stimulates RNA polymerase III-dependent transcription

摘要

BackgroundPNRC transcriptionally regulates a wide range of RNA polymerase (pol) II-transcribed genes by functioning as a nuclear receptor coactivator. To search for additional PNRC-interacting proteins other than nuclear receptors, a PNRC fragment was used as bait in a yeast two-hybrid screening of a human mammary gland cDNA expression library.