Height and Body Mass Index as Modifiers of Breast Cancer Risk in BRCA1/2 Mutation Carriers: A Mendelian Randomization Study

机译：身高和体重指数作为BRCA1 / 2突变携带者乳腺癌风险的改良剂：孟德尔随机研究

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Background BRCA1/2 mutations confer high lifetime risk of breast cancer, although other factors may modify this risk. Whether height or body mass index (BMI) modifies breast cancer risk in BRCA1/2 mutation carriers remains unclear.

机译：背景BRCA1 / 2突变赋予乳腺癌终生高风险，尽管其他因素可能会改变这种风险。身高或体重指数（BMI）是否会改变BRCA1 / 2突变携带者的乳腺癌风险仍不清楚。

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1. Height and Body Mass Index as Modifiers of Breast Cancer Risk in BRCA1/2 Mutation Carriers: A Mendelian Randomization Study [J] . Qian Frank, Wang Shengfeng, Mitchell Jonathan, Journal of the National Cancer Institute . 2019,第4期

机译：高度和体重指数作为BRCA1 / 2突变载体的乳腺癌风险的改性剂：孟德利安随机化研究
2. Common variants associated with breast cancer in genome-wide association studies are modifiers of breast cancer risk in BRCA1 and BRCA2 mutation carriers. [J] . Schmutzler RK, Wappenschmidt B, Engel C, Human Molecular Genetics . 2010,第14期

机译：全基因组关联研究中与乳腺癌相关的常见变异是BRCA1和BRCA2突变携带者中乳腺癌风险的修饰因子。
3. Common variants associated with breast cancer in genome-wide association studies are modifiers of breast cancer risk in BRCA1 and BRCA2 mutation carriers [J] . Xianshu Wang, V. Shane Pankratz, Zachary Fredericksen, Human Molecular Genetics . 2010,第14期

机译：全基因组关联研究中与乳腺癌相关的常见变异是BRCA1和BRCA2突变携带者中乳腺癌风险的修饰因子
4. Spectropolarimetric comparison of molecular-genetic study of BRCA1 gene mutation types in patients with breast cancer and their relatives [C] . O.P.Peresunko, T.V.Kruk, K.M.Chala, International Conference on Correlation Optics . 2020

机译：BRCA1基因突变类型在乳腺癌及其亲属患者中BRCA1基因突变类型的分子遗传学研究
5. Segregation analyses in Ashkenazi Jewish families: Evidence of an additional breast cancer susceptibility gene, and evaluation of cancer risks in BRCA1/2 mutation carriers. [D] . Kaufman, David J. 2002

机译：阿什肯纳兹犹太人家庭的隔离分析：另一个乳腺癌易感基因的证据，以及BRCA1 / 2突变携带者的癌症风险评估。
6. Mendelian randomisation study of height and body mass index as modifiers of ovarian cancer risk in 22588 BRCA1 and BRCA2 mutation carriers [O] . Frank Qian, Matti A. Rookus, Goska Leslie, 2019

机译：Mendelian随机性研究高度和体重指数作为22588 BRCA1和BRCA2突变载体的卵巢癌风险的调节剂
7. Common variants associated with breast cancer in genome-wide association studies are modifiers of breast cancer risk in BRCA1 and BRCA2 mutation carriers [O] . Wang, Xianshu, Pankratz, V. Shane, Fredericksen, Zachary, 2010

机译：全基因组关联研究中与乳腺癌相关的常见变异是BRCA1和BRCA2突变携带者中乳腺癌风险的修饰因子

Height and Body Mass Index as Modifiers of Breast Cancer Risk in BRCA1/2 Mutation Carriers: A Mendelian Randomization Study

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