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Persistence of Cytogenetic Abnormalities at Complete Remission After Induction in Patients With Acute Myeloid Leukemia: Prognostic Significance and the Potential Role of Allogeneic Stem-Cell Transplantation

机译：急性粒细胞白血病患者诱导后完全缓解后细胞遗传学异常的持续存在：预后意义和同种异体干细胞移植的潜在作用

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PurposeTo determine the prognostic impact of persistent cytogenetic abnormalities at complete remission (CR) on relapse-free survival (RFS) and overall survival (OS) in patients with acute myeloid leukemia (AML) and to examine the potential role of allogeneic stem-cell transplantation (SCT) in this setting.

机译：目的确定持久性细胞遗传学异常在完全缓解（CR）时对急性髓细胞性白血病（AML）患者的无复发生存期（RFS）和总体生存期（OS）的预后影响，并探讨同种异体干细胞移植的潜在作用（SCT）。

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期刊名称 Journal of Clinical Oncology
作者
Yiming Chen; Jorge Cortes; Zeev Estrov; Stefan Faderl; Wei Qiao; Lynne Abruzzo; Guillermo Garcia-Manero; Sherry Pierce; Xuelin Huang; Partow Kebriaei; Tapan Kadia; Marcos De Lima; Hagop Kantarjian; Farhad Ravandi;
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年(卷),期 -1(29),18
年度 -1
页码 2507–2513
总页数 7
原文格式 PDF
正文语种
中图分类肿瘤学;
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专利

1. Persistence of cytogenetic abnormalities at complete remission after induction in patients with acute myeloid leukemia: prognostic significance and the potential role of allogeneic stem-cell transplantation. [J] . Chen Y, Cortes J, Estrov Z, Journal of Clinical Oncology . 2011,第18期

机译：急性髓细胞性白血病患者诱导后完全缓解的细胞遗传学异常的持续性：预后意义和同种异体干细胞移植的潜在作用。
2. Influence of cytogenetic abnormalities on outcome after allogeneic bone marrow transplantation for acute myeloid leukemia in first complete remission. [J] . Chalandon Y, Barnett MJ, Horsman DE, Biology of blood and marrow transplantation: journal of the American Society for Blood and Marrow Transplantation . 2002,第8期

机译：首次完全缓解后，细胞遗传学异常对同种异体骨髓移植治疗急性髓性白血病后预后的影响。
3. Allogeneic stem cell transplantation in adult patients with acute myeloid leukaemia and 17p abnormalities in first complete remission: a study from the Acute Leukemia Working Party (ALWP) of the European Society for Blood and Marrow Transplantation (EBMT) [J] . Xavier Poiré, Myriam Labopin, Johan Maertens, Journal of Hematology and Oncology . 2017,第1期

机译：成年急性髓样白血病和首次完全缓解后17p异常的成年患者的同种异体干细胞移植：欧洲血液和骨髓移植学会（EBMT）急性白血病工作组（ALWP）的一项研究
4. Identification of Platelet Factor-4 as an Indicator of Blood Count Recovery in Acute Myeloid Leukemia Patients in Complete Remission [C] . Jin Young Kim, Ho-Jun Song, Hoi-Jeong Lim, ASMS Conference on Mass Spectrometry and Allied Topics . 2008

机译：血小板因子-4的鉴定为急性髓性白血病患者血统恢复的指标完全缓解
5. Evidence for heterogeneous genetic associations with acute lymphoblastic leukemia (ALL) by cytogenetics, age, and sex in high-risk patients treated with matched unrelated donor allogeneic blood or marrow transplant (URD-BMT) [D] . Clay, Alyssa I. 2016

机译：通过匹配的无关供体同种异体造血或骨髓移植（URD-BMT）治疗的高危患者中，通过细胞遗传学，年龄和性别进行的与急性淋巴细胞白血病（ALL）异质遗传关联的证据
6. Monosomal karyotype as an adverse prognostic factor in patients with acute myeloid leukemia treated with allogeneic hematopoietic stem-cell transplantation in first complete remission: a retrospective survey on behalf of the ALWP of the EBMT [O] . Angelique V.M. Brands-Nijenhuis, Myriam Labopin, Harry C. Schouten, 2016

机译：在首次完全缓解后接受异体造血干细胞移植治疗的急性髓细胞性白血病患者中染色体核型作为不良预后因素：代表EBMT的回顾性调查
7. Monosomal karyotype as an adverse prognostic factor in patients with acute myeloid leukemia treated with allogeneic hematopoietic stem-cell transplantation in first complete remission. A retrospective survey on behalf of the ALWP of EBMT [O] . Brands-Nijenhuis, Angelique., Labopin, Myriam, Schouten, Harry C., 2017

机译：在首次完全缓解后，接受同种异体造血干细胞移植治疗的急性髓细胞性白血病患者中，将染色体核型作为不良预后因素。代表EBMT的ALWP进行的回顾性调查

Persistence of Cytogenetic Abnormalities at Complete Remission After Induction in Patients With Acute Myeloid Leukemia: Prognostic Significance and the Potential Role of Allogeneic Stem-Cell Transplantation

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