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Genetic counselling for handicapped school leavers.

机译:残障学生的遗传咨询。

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摘要

A total of 287 school leavers with 299 unassociated handicaps from seven special schools for physically handicapped, visually handicapped, and deaf children were given genetic counselling from 1973 to 1979. The practical aspects of running this project are described. The risks needed were those of having an affected child: 54 (18.8%) were given a high risk (greater than 1 in 10), 89 (31.0%) were given a moderate risk (1 in 10 to 1 in 40), 69 (24.0%) were given a low risk (less than 1 in 40), and 83 (28.5%) were told that risk was the same as that of general population. Of the 299 total handicaps, 25 (8.4%) were thought to be autosomal dominant conditions, 38 (12.7%) to be autosomal recessive conditions, and 8 (2.7%) to be X linked conditions. Empirical risks were given for 145 (48.5%) diagnoses, and general population risks for the remaining 83 (27.7%).
机译:从1973年到1979年,对来自七所特殊学校的287名离校生和299名无残障儿童进行了遗传咨询。他们对七名残障,视障和聋哑儿童进行了遗传咨询。所需要的风险是生育孩子的风险:54(18.8%)为高风险(大于十分之一),89(31.0%)为中度风险(在十分之一至四十分之一),69 (24.0%)的风险低(不到40分之一),有83(28.5%)的风险被告知与一般人群相同。在299例总残障中,有25例(8.4%)被认为是常染色体显性遗传疾病,38例(12.7%)是常染色体隐性遗传疾病,8例(2.7%)是X连锁疾病。给出了145(48.5%)个诊断的经验风险,其余83个(27.7%)的诊断具有一般人群风险。

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