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Intraoperative cell salvage in revision hip surgery

机译:翻修髋关节手术中的术中细胞抢救

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摘要

Allogenic blood is a finite resource, with associated risks. Previous studies show intraoperative cell salvage (ICS) can reduce allogenic transfusion rates in orthopaedic surgery. However, there are concerns regarding efficacy and cost-effectiveness of ICS. This study was carried out to review ICS use in revision hip arthroplasty.All patients who underwent ICS and re-infusion between 2008 and 2010 in the Southern General Hospital (SGH) were audited. The fall in haemoglobin (Hb), volume of blood re-infused and postoperative allogenic transfusion rates were recorded. This group was compared to a similar SGH cohort who underwent surgery by the same surgeons between 2006 and 2008, and a pre-2005 control group where no ICS was used.The proportion of patients receiving a postoperative allogenic transfusion fell by 55% in the 2008–2010 ICS cohort compared with the control, and by 40% compared with the previous ICS group. In both instances, there was a statistically significant (p < 0.001) reduction in mean units transfused per patient; in the 2008–2010 ICS cohort, a mean of 0.8 units was used per patient, while 1.4 were used in the 2006–2008 cohort. 3.5 units were used in the control group. There was no statistically significant difference in age or preoperative Hb between the groups, or in length of hospital stay.In this study, ICS has been shown to be effective in reducing rates and volume of postoperative allogenic transfusion in patients undergoing revision hip surgery at the SGH. However, further work is needed to establish the effect of changing anaesthetic technique on postoperative allogenic transfusion rates.
机译:同种异体血液是一种有限的资源,具有相关的风险。先前的研究表明,术中细胞抢救(ICS)可以降低整形外科手术中的同种异体输血率。但是,人们担心ICS的功效和成本效益。这项研究的目的是回顾ICS在翻修髋关节置换术中的应用。对南方综合医院(SGH)在2008年至2010年之间接受ICS并再次输注的所有患者进行了审核。记录血红蛋白(Hb)下降,重新输注的血液量和术后同种异体输血率。将该组与在2006年至2008年之间由相同的外科医生进行手术的类似SGH队列以及不使用ICS的2005年前对照组进行比较.2008年接受异体输血的患者比例下降了55% –2010年ICS队列与对照组相比,比以前的ICS组增加了40%。在这两种情况下,每位患者输血的平均单位在统计学上有显着降低(p <0.001);在2008-2010年ICS队列中,每个患者平均使用0.8个单位,而在2006-2008年队列中使用1.4个单位。对照组使用3.5个单位。两组之间的年龄或术前Hb或住院时间无统计学差异。在这项研究中,ICS被证明可有效降低接受翻修手术的患者异体输血的速度和数量。 SGH。但是,还需要进一步的工作来确定改变麻醉技术对术后同种异体输血速率的影响。

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