Visceral Hypersensitivity and Altered Colonic Motility in Type 2 Diabetic Rat

机译：2型糖尿病大鼠的内脏超敏反应和结肠动力改变

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摘要

Background/AimsAbnormal visceral sensitivity and disordered motility are common in patients with diabetes mellitus. The purpose of the present study was to investigate whether visceral sensation and bowel motility were altered in a rat model of type 2 diabetes mellitus accompanied by weight loss.

机译：背景/目的糖尿病患者的内脏敏感性异常和运动异常是常见的。本研究的目的是研究在伴有体重减轻的2型糖尿病大鼠模型中内脏感觉和肠蠕动是否发生改变。

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期刊名称 Journal of Neurogastroenterology and Motility
作者
Tae Sik Sung; Jun-Ho La; Tong Mook Kang; Tae Wan Kim; Il-Suk Yang;
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作者单位

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年(卷),期 2015(21),4
年度 2015
页码 581–588
总页数 8
原文格式 PDF
正文语种
中图分类神经科学;
关键词
Abdominal withdrawal reflex Colonic dysmotility Colorectal distension Diabetes mellitus type 2 Visceral hypersensitivity;

机译：腹部退缩反射;结肠动力异常;结肠直肠扩张;糖尿病;2型;内脏超敏反应;

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专利

1. Modulation of enteric neurons by interleukin-6 and corticotropin-releasing factor contributes to visceral hypersensitivity and altered colonic motility in a rat model of irritable bowel syndrome [J] . Buckley Maria M., OHalloran Ken D., Rae Mark G., The Journal of Physiology . 2014,第23期

机译：白细胞介素6和促肾上腺皮质激素释放因子对肠神经元的调节有助于肠易激综合征的内脏超敏反应和结肠运动改变
2. Visceral hypersensitivity and altered colonic motility after subsidence of inflammation in a rat model of colitis [J] . Jun-Ho La, Tae-Wan Kim, Tae-Sik Sung, World Journal of Gastroenterology . 2003,第12期

机译：结肠炎大鼠模型发炎后内脏超敏反应和结肠运动改变
3. Activation of colonic mucosal 5-HT 4 receptors accelerates propulsive motility and inhibits visceral hypersensitivity [J] . HoffmanJ.M., TylerK., MacEachernS.J., Gastroenterology . 2012,第4期

机译：结肠粘膜5-HT 4受体的激活加速推进运动并抑制内脏超敏反应
4. A Mathematical Model of Visceral Hypersensitivity [C] . ROUSTEM MIFTAHOF WSEAS International Conferences . 2008

机译：内敏超敏反应的数学模型
5. Lactobacillus reuteri reduces visceral hypersensitivity and alters gut motility without changing gut serotonin availability in an animal model of the irritable bowel syndrome. [D] . Jakupovic, Jasmina. 2013

机译：在肠易激综合征的动物模型中，路氏乳杆菌可降低内脏超敏反应并改变肠蠕动，而不会改变肠内5-羟色胺的利用率。
6. Modulation of enteric neurons by interleukin-6 and corticotropin-releasing factor contributes to visceral hypersensitivity and altered colonic motility in a rat model of irritable bowel syndrome [O] . Maria M Buckley, Ken D OHalloran, Mark G Rae, 2014

机译：白细胞介素6和促肾上腺皮质激素释放因子对肠神经元的调节有助于肠易激综合征的内脏超敏反应和结肠运动改变
7. Visceral hypersensitivity and altered colonic motility after subsidence of inflammation in a rat model of colitis [O] . Jun-Ho La 2003

机译：在结肠炎大鼠大鼠模型中炎症后炎症后的内脏过敏和转子运动改变

Visceral Hypersensitivity and Altered Colonic Motility in Type 2 Diabetic Rat

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