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Extended spectrum beta lactamase producing organisms causing urinary tract infections in Sri Lanka and their antibiotic susceptibility pattern –A hospital based cross sectional study

机译:斯里兰卡引起尿道感染的广谱β-内酰胺酶生产菌及其抗生素敏感性模式–基于医院的横断面研究

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摘要

BackgroundExtended Spectrum Beta- Lactamase producing organisms causing urinary tract infections (ESBL-UTI) are increasing in incidence and pose a major burden to health care. While ESBL producing Klebsiella species seem to account for most nosocomial outbreaks, ESBL-producing E. coli have been isolated from both hospitalized and non-hospitalized patients. Although 95-100% ESBL organisms are still considered sensitive to meropenem, rapid emergence of carbapenem resistance has been documented in many countries. The objective of this study was to evaluate urinary tract infections caused by ESBL producers and the antibiotic susceptibility patterns in Sri Lanka.
机译:背景技术引起尿道感染(ESBL-UTI)的产生广谱β-内酰胺酶的生物的发病率正在增加,并给卫生保健带来了主要负担。虽然产生ESBL的克雷伯菌属占大多数医院内暴发的原因,但已从住院和非住院患者中分离出产生ESBL的大肠杆菌。尽管仍认为95-100%的ESBL生物对美洛培南敏感,但许多国家已有对碳青霉烯抗药性的快速出现。这项研究的目的是评估斯里兰卡ESBL生产商引起的尿路感染和抗生素敏感性模式。

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