The McNemar test for binary matched-pairs data: mid-p and asymptotic are better than exact conditional

摘要

BackgroundStatistical methods that use the mid-p approach are useful tools to analyze categorical data, particularly for small and moderate sample sizes. Mid-p tests strike a balance between overly conservative exact methods and asymptotic methods that frequently violate the nominal level. Here, we examine a mid-p version of the McNemar exact conditional test for the analysis of paired binomial proportions.