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The REVAMP study: research exploring various aspects and mechanisms in preeclampsia: study protocol

机译:REVAMP研究:探索先兆子痫各个方面和机制的研究:研究方案

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摘要

BackgroundPreeclampsia is a major cause of maternal, fetal and neonatal morbidity and mortality, particularly in developing countries. Considering the burden of preeclampsia and its associated complications, it is important to understand the underlying risk factors and mechanisms involved in its etiology. There is considerable interest in the potential for dietary long chain polyunsaturated fatty acids (LCPUFA) as a therapeutic intervention to prevent preeclampsia, as they are involved in angiogenesis, oxidative stress, and inflammatory pathways.
机译:背景先兆子痫是孕产妇,胎儿和新生儿发病率和死亡率的主要原因,尤其是在发展中国家。考虑到先兆子痫的负担及其相关的并发症,重要的是要了解其病因的潜在危险因素和机制。饮食中长链多不饱和脂肪酸(LCPUFA)作为预防先兆子痫的治疗手段的潜力引起了极大的兴趣,因为它们参与了血管生成,氧化应激和炎症途径。

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