Drug disposition and modelling before and after gastric bypass: immediate and controlled-release metoprolol formulations

机译：胃搭桥术前后的药物配置和模型：美托洛尔即刻和控释制剂

代理获取

本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。

页面导航

摘要
著录项
引文网络
相似文献
相关主题

摘要

AimsThe aim of the present study was to evaluate the disposition of metoprolol after oral administration of an immediate and controlled-release formulation before and after Roux-en-Y gastric bypass (RYGB) surgery in the same individuals and to validate a physiologically based pharmacokinetic (PBPK) model for predicting oral bioavailability following RYGB.

机译：目的本研究的目的是评估在同一个体的Roux-en-Y胃搭桥术（RYGB）手术前后口服速释和控释制剂后美托洛尔的处置情况，并验证基于生理的药代动力学（ PBPK）模型，用于预测RYGB后的口服生物利用度。

著录项

期刊名称 British Journal of Clinical Pharmacology
作者
Ina Gesquiere; Adam S Darwich; Bart Van der Schueren; Jan de Hoon; Matthias Lannoo; Christophe Matthys; Amin Rostami; Veerle Foulon; Patrick Augustijns;
展开▼
作者单位

展开▼
年(卷),期 2015(80),5
年度 2015
页码 1021–1030
总页数 10
原文格式 PDF
正文语种
中图分类药学;
关键词
controlled release disposition formulation metoprolol modelling Roux-en-Y gastric bypass;

机译：控释;处置;剂型;美托洛尔;模型;Roux-en-Y胃旁路;

相似文献

外文文献
中文文献
专利

1. Drug disposition and modelling before and after gastric bypass: immediate and controlled-release metoprolol formulations [J] . Gesquiere Ina, Darwich Adam S., Van der Schueren Bart, British Journal of Clinical Pharmacology . 2015,第5期

机译：胃搭桥术前后的药物配置和模型：美托洛尔即刻和控释制剂
2. Drug disposition and modelling before and after gastric bypass: immediate and controlled‐release metoprolol formulations [J] . Gesquiere Ina, Darwich Adam S., Van der Schueren Bart, British journal of clinical pharmacology . 2015,第5期

机译：胃搭桥术前后的药物处置和模型：即时和控释美托洛尔制剂
3. Disposition of different formulations of metoprolol before and after gastric bypass [J] . Gesquiere Ina, Van der Schueren Bart, Lannoo Matthias, International journal of clinical pharmacy. . 2015,第1期

机译：胃旁路术前后美托洛尔不同配方的处置
4. Gastric Processing is a Critical Determinant of the Ability of Lipid-Based Formulations to Enhance the Oral Bioavailability of a Model Poorly Water-Soluble Drug [C] . Annual meeting exposition of the Controlled Release Society . 2009

机译：胃加工是脂质的制剂能力提高模型水溶性药物的口腔生物利用度的关键决定因素
5. (1) Development and in vivo testing of a gastric retention device (GRD) in dogs, (2) Product formulations and in vitro-in vivo evaluation of, (a) immediate release formulation of itraconazole, (b) controlled-release formulation of ketoprofen in adults [D] . Kapsi, Shivakumar G. 1999

机译：（1）在犬中开发胃滞留装置（GRD）并进行体内测试；（2）（a）伊曲康唑的速释制剂，（b）依他康唑的控释制剂的产品配方和体内体外评估成人酮洛芬
6. Formulation of Controlled-Release Capsules of Biopharmaceutical Classification System I Drugs Using Niacin as a Model [O] . Monica C. Chuong, Luca Palugan, Tiffany M. Su, 2010

机译：以烟酸为模型的生物药物分类系统I药物的控释胶囊剂的研制
7. Drug disposition and modelling before and after gastric bypass: immediate and controlled-release metoprolol formulations [O] . Gesquiere Ina, Darwich Adam S, Van Der Schueren Bart, 2015

机译：胃搭桥术前后的药物配置和模型：美托洛尔即刻和控释制剂

Drug disposition and modelling before and after gastric bypass: immediate and controlled-release metoprolol formulations

摘要

著录项

引文网络

相似文献

相关主题

期刊订阅