Serum concentrations of tramadol enantiomers during patient-controlled analgesia

摘要

AimsTramadol, a centrally acting analgesic, is used as a racemate containing 50% of a (+)- and 50% of a (−)-enantiomer. This paper presents the pharmacokinetic results of postoperative patient-controlled analgesia using (+)-tramadol, (−)-tramadol or the racemate.