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Downregulation of hsa_circ_0011946 suppresses the migration and invasion of the breast cancer cell line MCF-7 by targeting RFC3

机译:hsa_circ_0011946的下调通过靶向RFC3抑制乳腺癌细胞系MCF-7的迁移和侵袭

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摘要

IntroductionAlthough some circRNAs have been found to regulate the progression of malignancies, their functions and coupled molecular mechanisms are still unclear. In our study, we sought to assess the underlying molecular mechanisms of circRNAs in breast cancer and therefore explored the differentially expressed circRNAs and co-expression networks, followed by in vitro experiments.
机译:引言尽管已发现一些circRNA可以调节恶性肿瘤的进展,但其功能和耦合的分子机制仍不清楚。在我们的研究中,我们试图评估circRNA在乳腺癌中的潜在分子机制,因此探索了差异表达的circRNA和共表达网络,然后进行了体外实验。

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