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Secondary adrenal insufficiency after glucocorticosteroid administration in acute spinal cord injury: A case report

机译:糖皮质激素治疗急性脊髓损伤后继发性肾上腺功能不全:一例

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摘要

Context/backgroundA 61-year-old female with cervical stenosis underwent an elective cervical laminectomy with post-op worsening upper extremity weakness. Over the first 3 weeks post-op, she received two separate courses of intravenous steroids. Two days after cessation of steroids, she presented with non-specific symptoms of adrenal insufficiency (AI). Initial formal diagnostic tests of random cortisol level and 250 µg cosyntropin challenge were non-diagnostic; however, symptoms resolved with the initiation of empiric treatment with hydrocortisone. Ten days later, repeat cosyntropin (adrenocortocotropic hormone stimulation) test confirmed the diagnosis of AI.
机译:背景/背景:一名61岁的女性宫颈狭窄患者接受了选择性宫颈椎板切除术,手术后上肢无力恶化。在手术后的前三周,她接受了两个单独的静脉类固醇疗程。停用类固醇两天后,她出现了肾上腺功能不全(AI)的非特异性症状。最初的正式诊断测试是随机诊断皮质醇水平和250μg促肾上腺皮质激素的水平,不能诊断。但是,通过氢化可的松开始经验性治疗可以缓解症状。十天后,重复进行促肾上腺皮质激素(促肾上腺皮质激素刺激)试验证实了AI的诊断。

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