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Monoclonal antibody AC10364 inhibits cell proliferation in 5-fluorouracil resistant hepatocellular carcinoma via apoptotic pathways

机译：单克隆抗体AC10364通过细胞凋亡途径抑制5-氟尿嘧啶耐药肝细胞癌中的细胞增殖

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BackgroundThis study was designed to investigate the antitumor activity of the mAb (AC10364) in vitro and elucidate the related mechanisms of inhibition to cell growth using bel/fu cells treated with AC10364.

机译：背景本研究旨在研究mAb（AC10364）的体外抗肿瘤活性，并阐明使用AC10364处理的bel / fu细胞抑制细胞生长的相关机制。

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期刊名称 OncoTargets and therapy
作者
Jianzhong Wu; Junwei Qu; Haixia Cao; Changwen Jing; Zhuo Wang; Heng Xu; Rong Ma;
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作者单位

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年(卷),期 2019(12),-1
年度 2019
页码 5053–5067
总页数 15
原文格式 PDF
正文语种
中图分类应用微生物学;肿瘤学;
关键词
monoclonal antibody inhibitory apoptosis genes;

机译：单克隆抗体;抑制;凋亡;基因;

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专利

1. Monoclonal antibody AC10364 inhibits cell proliferation in 5-fluorouracil resistant hepatocellular carcinoma via apoptotic pathways [J] . Jianzhong Wu, Junwei Qu, Haixia Cao, OncoTargets and therapy . 2019,第2期

机译：单克隆抗体AC10364通过细胞凋亡途径抑制5-氟尿嘧啶耐药肝细胞癌中的细胞增殖
2. Opsin3 sensitizes hepatocellular carcinoma cells to 5-fluorouracil treatment by regulating the apoptotic pathway [J] . JiaoJ., HongS., ZhangJ., Cancer letters . 2012,第1期

机译：Opsin3通过调节细胞凋亡途径使肝癌细胞对5-氟尿嘧啶治疗敏感
3. Immunization with UV-induced apoptotic cells generates monoclonal antibodies against proteins differentially expressed in hepatocellular carcinoma cell lines. [J] . Celikkaya H, Ciraci C, Oztas E, Hybridoma . 2007,第2期

机译：用紫外线诱导的凋亡细胞免疫产生针对在肝癌细胞系中差异表达的蛋白质的单克隆抗体。
4. An Envelop-Type Gene Nanocomplex with Encapsulated Monoclonal Antibodies for Target Therapy of Hepatocellular Carcinoma [C] . Wang Jinlei, Shen Jie, Hu Qinglian, World biomaterials congress . 2012

机译：信封型基因纳米复合物与封装的单克隆抗体对肝细胞癌的靶向治疗
5. Cannabinol Inhibits Proliferation and Induces Cell Cycle Arrest and Apoptosis in Glioblastoma, Hepatocellular Carcinoma and Breast Cancer Cells [D] . Zhong, Nuanying. 2020

机译：大麻素抑制胶质母细胞瘤，肝细胞癌和乳腺癌细胞中的增殖和诱导细胞周期停滞和凋亡
6. Amyloid precursor protein regulates 5-fluorouracil resistance in human hepatocellular carcinoma cells by inhibiting the mitochondrial apoptotic pathway [O] . Xiao-long Wu, Ying Chen, Wen-cui Kong, 2020

机译：淀粉样蛋白前体蛋白通过抑制线粒体凋亡途径调节人肝癌细胞中的5-氟尿嘧啶抗性
7. Immunization with UV-induced apoptotic cells generates monoclonal antibodies against proteins differentially expressed in hepatocellular carcinoma cell lines [O] . Celikkaya H., Ciraci, C., Oztas, E., 2007

机译：用紫外线诱导的凋亡细胞免疫产生针对肝细胞癌细胞系中差异表达的蛋白质的单克隆抗体

Monoclonal antibody AC10364 inhibits cell proliferation in 5-fluorouracil resistant hepatocellular carcinoma via apoptotic pathways

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