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Comparative clinical feasibility study of three tools for delivery of cognitive behavioural therapy for mild to moderate depression and anxiety provided on a self‐help basis

机译:自助提供三种用于轻度至中度抑郁和焦虑的认知行为治疗工具的比较临床可行性研究

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摘要

>Background In response to a research recommendation made by a UK healthcare policy agency (National Institute for Health and Clinical Excellence (NICE)), this study compared the effectiveness of computer‐based cognitive behavioural therapy (CBT) with other self‐help treatment options for mild to moderate depression and anxiety.>Method Comparative, clinical feasibility study of three self‐help CBT tools with six‐month follow‐up. Out of an initial sample of 180 adults referred by their general practitioners, 100 met the inclusion criteria and after consenting to take part were allocated one of three self‐help CBT tools: the Beating the Blues® (BtB) computer programme; workbooks on overcoming depression and anxiety; and the Livinglifetothefull free access internet website.>Results Only 50 of the 100 consented participants completed the allocated intervention protocols, however, drop‐out rates were not significantly different between the groups of participants allocated each of the three self‐help CBT tools. Adults aged over 24 years (χ2 = 14.5; df = 2; P = 0.001) and with symptom duration greater than four years (χ2 = 3.96; df = 1; P = 0.047) were significantly more likely to complete any of the three interventions. There was a highly significant reduction in mean Clinical Outcomes in Routine Evaluation–Outcome Measure (CORE–OM) score at week eight compared to entry in all three groups (t (49) = 9.150; P ≤0.001). Adjusting for entry scores, there was no significant difference between the three groups in CORE–OM score improvement at week eight. There was no significant association between CORE–OM score improvement at week eight and number of general practitioner (GP) consultations at six months. There was no significant association between whether participants completed the programme and number of GP consultations at six months.>Conclusions The results demonstrated that within a two‐month follow‐up period, three different tools delivering self‐help CBT all produced significant clinical benefit for adults with mild to moderate depression and anxiety. The study had limited statistical power, but none of the modalities for delivering supported self‐help CBT appeared superior to another. There was no evidence to suggest that any of these interventions would be likely to reduce subsequent service uptake. Nevertheless, this pilot study has shown sufficient benefit from each of the self‐administered CBT tools to justify larger trials of their use.
机译:>背景为了回应英国医疗政策机构(国家卫生与临床卓越研究所(NICE))提出的研究建议,本研究将基于计算机的认知行为疗法(CBT)与其他针对轻度至中度抑郁和焦虑的自助治疗选择。>方法三种自助CBT工具的临床比较可行性研究,为期6个月的随访。在他们的全科医生转诊的180位成年人的初始样本中,有100位符合纳入标准,并在同意参加之后被分配了三种自助CBT工具之一:Beating theBlues®(BtB)计算机程序; 有关克服抑郁和焦虑的工作手册; >结果。在同意的100位参与者中,只有50位完成了分配的干预方案,但是,两组之间的辍学率没有显着差异。参与者分配了三种自助CBT工具。年龄超过24岁的成年人(χ 2 = 14.5; df = 2; P = 0.001)并且症状持续时间大于四年(χ 2 = 3.96; df = 1 ; P = 0.047)更有可能完成这三种干预措施中的任何一项。与所有三个组的入组相比,第8周的例行评估-结局测量(CORE-OM)评分的平均临床结局均显着降低(t(49)= 9.150; P≤0.001)。调整入学分数后,三组在第8周的CORE–OM分数改善方面无显着差异。第八周的CORE-OM评分改善与六个月的全科医生(GP)咨询次数之间没有显着关联。参与者是否完成该计划与六个月的全科医生咨询次数之间没有显着关联。>结论结果表明,在两个月的随访期内,三种不同的工具可提供自助式CBT所有这些都对患有轻度至中度抑郁症和焦虑症的成年人产生了显着的临床益处。这项研究的统计能力有限,但是提供支持的自助式CBT的任何一种方法似乎都不比其他方法优越。没有证据表明这些干预措施中的任何一种都有可能减少随后的服务使用。但是,该初步研究表明,每种自我管理的CBT工具都具有足够的优势,可以证明对其使用进行了较大的试验。

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