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Neuroendocrine tumour arising inside a retro-rectal tailgut cyst: report of two cases and a review of the literature

机译:直肠后尾肠囊肿内发生神经内分泌肿瘤:两例报告并文献复习

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摘要

Tailgut cysts (or retro-rectal cyst-hamartomas (RCHs)) are developmental abnormalities consisting of multiloculated cysts lined by squamous, transitional or glandular epithelium which, albeit rarely, may give rise to malignant transformations. Carcinoid tumours arising in the presacral region are extremely rare and usually benign, and only a few are described in the literature. Case 1: A 63-year-old female diagnosed as having bilateral ovarian cysts underwent surgery to remove a right adnexial mass that was histopathologically diagnosed as a well-differentiated carcinoid tumour. She is currently disease free after 18 months of follow-up. Case 2: A 41-year-old-female diagnosed with hepatic metastases and a solid pelvic mass arising from a moderately differentiated neuroendocrine carcinoma is currently alive with disease after having undergone surgical removal of the mass and several medical treatments. We here describe two different clinical histories of well- and moderately differentiated neuroendocrine tumours (NETs) arising from tailgut cysts in the prerectal space together with a review of the relevant literature.
机译:尾牙囊肿(或直肠后囊肿-瘤构瘤(RCH))是发育异常,由鳞状上皮,过渡上皮或腺上皮衬砌的多位置囊肿组成,尽管这种情况很少,但可能引起恶性转化。在s前区域出现的类癌肿瘤非常罕见,通常是良性的,文献中仅描述了少数。病例1:一名63岁女性,被诊断患有双侧卵巢囊肿,接受了手术以切除右附件,该附件在组织病理学上被诊断为高分化类癌。经过18个月的随访,她目前没有疾病。病例2:一名41岁的女性,由于中度分化的神经内分泌癌而被诊断出肝转移和盆腔实性肿块,在经过外科手术切除肿块并接受数种药物治疗后,目前仍存活。我们在这里描述了由直肠前间隙尾肠囊肿引起的中分化神经内分泌肿瘤(NETs)的两种不同的临床历史,并回顾了相关文献。

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