丽水地区儿童幽门螺旋杆菌感染临床分析

摘要

Objective To analyze the infection situation and characteristics of Helicobacter pylori (HP) in children,and to do a good job of prevention in order to reduce the infection rate of HP in children in this area. Method The data of children with gastrointestinal symptoms who were visited our hospital from January 2014 to December 2017 were collected. 0-14 years old,rapid detection of serum Helicobacter pylori antigen antibody, the results were statistically analyzed. Result The detection rate of HP in 200 children aged 0-14 years was 21%(42/200),There were no significant differences in the infection rates between male and female(23.28%,27/116 and 17.86%,15/84)(χ2=0.862,P>0.05). The detection rate of Hp in children aged 0-14 was different(χ2tender=4.181,P=0.041),and the detection rate of Hp in children with parental infection with Hp or the history of gastrointestinal diseases was higher(χ2=4.314、4.191,P<0.05). Conclusion The detection rate of Helicobacter pylori in children with digestive tract symptoms was higher,and the infection rate increased with age. At the same time,there was a significant familial clustering of Helicobacter pylori in children. Therefore,clinicians should pay attention to Helicobacter pylori infection in children,quickly find the cause of child discomfort, timely diagnosis and treatment.%目的 分析儿童幽门螺旋杆菌(HP)感染情况及感染特点,为进一步降低本地区儿童感染幽门螺旋杆菌感染率做好预防工作.方法 收集2014年1月到2017年12月有消化道症状的儿童200例.年龄0~14周岁,快速检测血清幽门螺旋杆菌现症感染标志抗体和总抗体,对结果进行统计分析.结果 200例儿童幽门螺旋杆菌感染检出率21%,其中男、女感染率分别为23.28%、17.86%,差异无统计学意义(χ2=0.862,P>0.05),各年龄段儿童幽门螺旋杆菌检出率差异有统计学意义(χ2趋势=4.181,P=0.041),父母感染幽门螺旋杆菌或有胃肠疾病史的家庭,儿童幽门螺旋杆菌检出率高,差异有统计学意义(χ2=5.880、6.050,P<0.05).结论 有消化道症状的儿童幽门螺旋杆菌检出率较高,随着年龄增长感染率呈升高趋势,同时儿童幽门螺旋杆菌有明显的家族聚集性.因此,临床医师应重视儿童幽门螺旋杆菌感染,快速找到儿童腹部不适的病因,及时诊治.