七氟烷复合瑞芬太尼用于老年胃癌根治术的临床价值

摘要

Objective To study the clinical experience of sevoflurane combined with remifentanil in radical gastrectomy for elderly patients with gastric cancer. Methods 60 elderly patients with gastric cancer underwgone radical gastrectomy were randomly divided into two groups,30 cases in each group.The observation group received sevoflurane combined with remifentanil anesthesia,and the control group received isoflurane combined with remifentanil anesthesia.The hemodynamic indexes of two groups were recorded,and the anesthetic effects and adverse reactions of the two groups were compared. Results There were no significant difference in MAP and HR between the two groups at each time point in operation(P>0.05).The MAP and HR were significantly lower than those before anesthesia induction immediately after tracheal intubation(P<0.05). The recovery time and extubation time of the observation group were significantly shorter than those of the control group(P<0.05). After extubation,the recovery effect score of the observation group was significantly better than that of the control group 10min(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05). Conclusion The sevoflurane combined with remifentanil is safe and reliable for elderly patients undergoone radical gastrectomy for gastric cancer,and maintains hemodynamic stability during surgery which helps patients recover early.%目的 研究七氟烷复合瑞芬太尼用于老年胃癌根治术的临床体会.方法 纳入60例老年胃癌根治术患者作为观察对象,随机抽签分为两组,每组各30例.观察组行七氟烷复合瑞芬太尼麻醉,对照组行异氟烷复合瑞芬太尼麻醉.记录两组术中血流动力学指标变化情况,比较两组麻醉效果及不良反应.结果 两组术中各时间点MAP和HR无显著性差异(P>0.05),气管插管即刻MAP和HR均显著低于麻醉诱导前(P<0.05).观察组苏醒和拔管时间均显著短于对照组(P<0.05),拔管后10min时观察组苏醒效果评分显著优于对照组(P<0.05).两组不良反应发生率无显著性差异(P>0.05).结论 七氟烷复合瑞芬太尼用于老年胃癌根治术患者,可获得安全可靠的麻醉效果,维持术中血流动力学的稳定,有助于患者早期康复.