Objective To investigate the prevalence of insomnia and the factors related to insomnia in maintenance hemodialysis (MHD) patients in our hemodialysis center. Methods Sixty-five patients on MHD were investigated in this study. Patients were evalu-ated by the Athens Insomnia Scale (AIS), Pittsburgh Sleep Quality Index (PSQI) and Epworth Sleepiness Scale (ESS). General state (gender, smoking, drinking tea or coffee, hypertension, diabetes, cutaneous pruritus, nocturnal leg muscle cramp), dialysis data (age, du-ration of hemodialysis, time of hemodialysis per week) and biochemical parameters (albumin, serum creatinine, blood urea nitrogen, hemoglobin, calcium-phosphorus product, parathormone, Ultra-sensitive C-reactive protein, serum iron) were collected at the same time. Patients were divided into two groups: with insomnia (AIS score≥6) and without insomnia (AIS score<6). Results (1) The in-somnia prevalence was 46.2% obtained from questionnaire. (2) The PSQI score of insomnia group was higher than that of group without insomnia (P<0.01). (3) Incidence rate of cutaneous pruritus and diabetes in insomnia group were higher than that of group without in-somnia (P<0.01). (4) There were significant differences in age and serum albumin levels between the two groups (P<0.05). Conclusion The prevalence of insomnia in MHD patients in our hemodialysis center was 46.2%. Older age, cutaneous pruritus, diabetes and serum albumin levels were the relevant factors for insomnia.%目的：：通过对安徽省第二人民医院维持性血液透析患者睡眠情况及部分相关因素进行调查，分析血液透析患者失眠的发生情况及影响因素。方法：对我院65例透析龄≥6个月，病情稳定的血液透析患者进行调查研究。分别采用阿森斯失眠量表（AIS）、匹兹堡睡眠质量指数（PSQI）、Epworth 嗜睡量表（ESS）进行评估。同时记录患者的一般状况（性别、吸烟、喝茶/咖啡、高血压、糖尿病、皮肤瘙痒、夜间腿部肌肉痉挛），透析参数（年龄、透析龄、每周透析时间）以及部分生化指标（白蛋白、血肌酐、尿素氮、血红蛋白、钙磷乘积、甲状旁腺激素、超敏 C 反应蛋白、血清铁）。以 AIS≥6分评定为失眠，将被调查患者分为失眠组与非失眠组，对两组之间指标进行统计学分析。结果：（1）失眠者占血液透析患者的46．2%；（2）失眠组 PSQI 评分显著高于非失眠组（P＜0．01）；（3）两组相比，失眠组患者皮肤瘙痒发生率、糖尿病患病率显著高于非失眠组（P＜0．01）；（4）失眠组与非失眠组患者在年龄及血浆白蛋白水平方面存在显著差异（P＜0．05）。结论：本院血液透析室病情稳定的维持性血液透析患者失眠率达46．2%。年龄、皮肤瘙痒、合并糖尿病、血浆白蛋白水平是影响患者睡眠障碍的相关因素。
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