糖肾灌肠方治疗糖尿病肾病慢性肾功能不全临床疗效观察

摘要

目的:探讨糖肾灌肠方治疗糖尿病肾病肾功能不全的临床疗效.方法:选择2014年6月至2015年10月住院就诊的糖尿病肾病肾功能不全患者94例,按随机数字表法将研究对象分为治疗组和对照组,2组患者给予低盐低脂优质蛋白饮食,采取胰岛素控制血糖,配合ARB类降压药物,治疗组在上述治疗基础上使用糖肾灌肠方,对照组则加用肾衰康灌肠液治疗,疗程3个月后观察2组患者治疗前后的血糖、血压、24 h尿蛋白定量、肾功能、血浆白蛋白及中医症候评分.结果:治疗组的中医症候疗效总有效率明显优于对照组,治疗组治疗后实验室各项指标改善明显,对照组治疗后较治疗前改善不明显,治疗组治疗后症状积分下降明显,而对照组下降不明显.结论:糖肾灌肠方联合西药治疗糖尿病肾病肾功能不全的疗效优于肾衰康灌肠液联合西药治疗,可有效降低各项监测指标,改善患者的营养状况,消除水肿,改善肾功能,提高患者的生存质量.%Objective:To discuss Tangshen Guanchang Decoction clinical curative effect for the treatment of diabetic nephropathy renal insufficiency.Methods:Ninety-four patients with renal insufficiency due to diabetic nephropathy who received treatment in the hospital from June 2014 to October 2015 were selected and randomly divided into treatment group and control group,according to random number table method.Patients in both the two groups were given low salt-fat and high protein diet,insulin to control blood sugar and ARB antihypertensive drugs.Patients in the treatment group additionally adopted Tangshen Guanchang Decoction on the basis of the above treatment,while patients in the control group were treated with Shenshuaikang enema for 3 months.Blood glucose,blood pressure,24 hours urinary protein,renal function,plasma albumin and quantitative TCM symptom score of patients in the two groups before and after treatment were observed.Results:Total effective rate for the TCM symptoms of the treatment group was obviously better than that of the control group.Laboratory indicators of the treatment group improved obviously after the treatment,while improvement of the control group after treatment was not obvious.Symptoms integral of the treatment group after treatment decreased significantly,while that of the control group was not obvious.Conclusion:The curative effect of Tangshen Guanchang Decoction combined with western medicine in treating renal insufficiency due to diabetic nephropathy of is better than that of r Shenshuaikang enema combined western medicine therapy and may effectively reduce lab indicators,improve patients′ nutritional status and renal function,relieve dropsy,and enhance patients′ quality of life.