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Agonists of A2A Adenosine Receptors for Treatment of Diabetic Nephropathy.

机译：a2a腺苷受体激动剂治疗糖尿病肾病。

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The present invention provides a therapeutic method for treating diabetic kidney disease, e.g., diabetic nephropathy that includes the administration of an effective amount of an A(sub 2A) adenosine receptor agonist. Optionally, the method includes administration of a type IV PDE inhibitor.

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Okusa, M. D.; Linden, J. M.; Macdonald, T. L.; Awad, A. S.;
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年度 2005
页码 1-43
总页数 43
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Diabetic nephropathy; Adenosine receptors; Patent applications; Agonists; Diabetes; End stage renal disease; A2A adenosine receptor agonist;

机译：糖尿病肾病;腺苷受体;专利申请;激动剂;糖尿病;终末期肾病; a2a腺苷受体激动剂;

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专利

1. Effects of adenosine and adenosine A2A receptor agonist on motor nerve conduction velocity and nerve blood flow in experimental diabetic neuropathy. [J] . Kumar S, Arun KH, Kaul CL, Neurological Research: An Interdisciplinary Quarterly Journal . 2005,第1期

机译：腺苷和腺苷A2A受体激动剂对实验性糖尿病神经病患者运动神经传导速度和神经血流的影响。
2. Adenosine A2A receptor activation attenuates inflammation and injury in diabetic nephropathy. [J] . Awad AS, Huang L, Ye H, American Journal of Physiology . 2006,第4期

机译：腺苷A2A受体激活可减轻糖尿病肾病的炎症和损伤。
3. Effects of adenosine A2A receptor low affinity agonist Regadenoson in patients with obstructive pulmonary disease, at risk for adenosine-induced bronchoconstriction mediated via A2B and/or A3 adenosine receptors. [J] . Stefan Meyering, Harry Lomas The Internet Journal of Cardiovascular Research . 2008,第2期

机译：腺苷A2A受体低亲和力激动剂Regadenoson对有阻塞性肺疾病的患者的影响，这些患者有通过A2B和/或A3腺苷受体介导的腺苷诱导的支气管狭窄风险。
4. The selective antagonism of A2A adenosine receptors prevents synaptic failure induced by oxygen and glucose deprivation in rat dentate gyrus [C] . Maraulaa G., Trainia C., Mellob T., European Congress of Pharmacology . 2012

机译：A2A腺苷受体的选择性拮抗剂可防止氧气牙齿诱导的氧气失败和葡萄糖剥夺的突触失败
5. A potential treatment for insomnia by positive allosteric modulation of adenosine A2A receptors [D] . Mustafa Korkutata 2019

机译：腺苷A2A受体的正构变构调节对失眠的潜在治疗
6. Binding of the prototypical adenosine A2A receptor agonist CGS 21680 to the cerebral cortex of adenosine A1 and A2A receptor knockout mice [O] . Luísa V Lopes, Linda Halldner, Nelson Rebola, 2004

机译：原型腺苷A2A受体激动剂CGS 21680与腺苷A1和A2A受体敲除小鼠的大脑皮层的结合
7. Binding of the prototypical adenosine A2A receptor agonist CGS 21680 to the cerebral cortex of adenosine A1 and A2A receptor knockout mice [O] . Lopes, Luísa V, Halldner, Linda, Rebola, Nelson, 2004

机译：原型腺苷A2A受体激动剂CGS 21680与腺苷A1和A2A受体敲除小鼠的大脑皮层的结合

Agonists of A2A Adenosine Receptors for Treatment of Diabetic Nephropathy.

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