脑心同治法对老年卒中后失眠患者总体睡眠状态及失眠药物剂量的影响

摘要

Objective:To observe the effect of Brain-hear concurrent regulation therapy on sleeping quality and hypnotic dosage in elder patients with insomnia after stoke.Methods:To collect 100 cases of elder patients who has insomnia after stroke of Yin-deficiency and Exuberant-fire type.Then randomly divided them into two groups with 50 in each.The control group was given Estazolam and regular western medicine,and the treatment group was given Huanglian Ejiao decoction on the basis of that.The treatment course is one month.Sleeping quality and hypnotic dosage were compared between the two groups.PSQI,ISI,HAMA,HAMD scores were used to assess their emotion improvement.Adverse reactions were also observed.Results:The total effective rate of the treatment group is 92.00%,higher than 76.00% of the control group(P<0.05).After treatment,the treatment group gains the scores of PSQI (5.26±0.69),ISI (9.50±1.64),HAMA (9.87±1.59),and HAMD (10.25±1.88).All lower than those of the control group (P<0.05).The adverse reaction rate of the treatment group is 10.00%,while without significant difference with the control group 6.00% (P>0.05).Conclusion:The concurrent therapy of Brain-heart can improve the sleeping quality of target patients,decrease the dosage of hypnotic without inducing further adverse reactions.It is applicable in clinical practice.%目的:探讨脑心同治法对阴虚火旺型老年卒中后失眠患者总体睡眠状态及失眠药物剂量的影响.方法:选取2010年3月至2015年10月我院收治的阴虚火旺型老年卒中后失眠患者100例为研究对象,采用随机数表法分为观察组和对照组各50例,对照组给予艾司唑仑、常规西药治疗,观察组在此基础上给予黄连阿胶汤,2组均治疗1个月,对比其治疗有效率及失眠药剂量,应用匹茨堡睡眠质量指数量表(PSQI)、失眠严重程度指数(ISI)评价其睡眠状态,同时采用汉密尔顿焦虑量表(HAMA)、汉密尔顿抑郁量表(HAMD)评价2组情绪改善情况,并观察不良反应.结果:观察组治疗有效率92.00%明显高于对照组76.00%(P<0.05);治疗后观察组PSQI评分(5.26±0.69)分、ISI评分(9.50±1.64)分、HAMA评分(9.87±1.59)分、HAMD评分(10.25±1.88)分较对照组低(P均<0.05);观察组不良反应发生率10.00%与对照组6.00%比较无统计学意义(P>0.05).结论:脑心同治法可有效改善老年卒中后失眠患者总体睡眠状态,降低其失眠药用药剂量,且不会增加西药不良反应,值得在临床推广应用.