微流体芯片可在微通道中控制、操作和检测复杂流体,具有尺寸小、效率高、集成度高、响应时间短、样品需量少等优点.除了在生物化学、有机合成、疾病检测等领域有广泛的应用之外,微流体芯片在纤维成型方面也有很大的应用潜力.在简介了微流体技术的基础上,比较了传统纺丝技术和微流体纺丝技术,综述了微流体芯片在即时纺丝、静电纺丝和蛋白质成纤方面的研究进展,展望了微流体纺丝技术在高性能纤维、纳米纤维、生物/化学纳米传感器、组织工程等方面的应用前景.%Mierofluidic chips can control, operate and detect complex fluids in microscale channels. Such microsystems have been shown to have many advantages, such as small in size, high efficiency, high integration and fast response time, small quantity sample demanded, fast response time, and high integration. In addition to a variety of applications in biochemistry, organic synthesis and disease diagnosis, fiber formation becomes a great potential application of microfiuidic chip. On the basis of the micmfiuidic technology, traditional spinning process is compared with microfluidic spinning technology. The research progresses of microfiuidic chip in on the fly spinning,electrospinning and fabrication of protein fibers are reviewed. The applications of microfluidic spinning including high performance fiber, nanofiber, bio-chemical nano-sensors, and tissue engineering are prospected.
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