离子液体中微波辅助水杨酸酯的合成

摘要

在微波辐射功率为250 W反应25 min的条件下,水杨酸分别与甲醇、乙醇、丙醇、异丙醇、叔丁醇在离子液体作溶剂和催化剂下发生酯化反应,得到了水杨酸甲酯、水杨酸乙酯、水杨酸丙酯、水杨酸异丙酯、水杨酸叔丁酯,收率85.95%,产物结构经1H NMR和元素分析进行了确认.%Using NaHSO4 · H2O as the catalyst, five important organic intermediates, methyl chloroacetate, ethyl chloroacetate, n-propyl chloroacetate, iso-propyl chloroacetate and tert-butyl chloroacerate were obtained in 76％-91％ yields from chloroacetic acid and the corresponding alcohols under microwave irradiation at 250 W for 10 min. All products were identified by 1 H NMR, and elementary analysis.