拔罐辅助治疗非酒精性脂肪性肝病临床疗效观察

摘要

目的 通过拔罐干预,观察非酒精性脂肪性肝病(nonalcoholic fatty liver disease,NAFLD)患者的临床疗效,并进一步探索其可能存在的机制.方法 选取50例NAFLD患者,随机分成两组,治疗组(25例,拔罐+中药+饮食+运动联合疗法)和对照组(25例,中药+饮食+运动联合疗法),经过6个月的临床观察后,记录所有患者治疗前后的体重、体质指数(body mass index,BMI)、腹围、臀围、臂围、腿围、血脂(包括总胆固醇TC,甘油三酯TG)、肝酶(包括谷草转氨酶AST,谷丙转氨酶ALT)、肝脏B超的变化,并进行统计学分析.结果 治疗组和对照组经过6个月的治疗,所有患者体重、BMI、腹围、臀围、臂围、腿围均明显改善(P<0.05);部分患者TC、TG、AST、ALT降至正常范围,肝脏B超转阴;治疗组患者腹围较对照组明显缩小,差异有统计学意义(P<0.05).结论 拔罐联合中药、饮食、运动综合治疗可有效改善NAFLD患者临床观察指标,尤其是腹型肥胖者效果最佳.%Objective To observe the clinical efficacy of cupping in intervening non-alcoholic fatty liver disease (NAFLD), and further explore the possible mechanism. Method Fifty NAFLD patients were randomized into two groups: a treatment group (25 cases, intervened by cupping, Chinese medication, diet control and kinesiotherapy) and a control group (25 cases, intervened by Chinese medication, diet control and kinesiotherapy). They were observed for 6 months. Body weight, body mass index (BMI), abdomen circumference, hip circumference, arm circumference, thigh circumference, blood lipids [including total cholesterol (TC) and triglyceride (TG)], hepatic enzymes [including aspartate transaminase (AST) and alanine transaminase (ALT)], and B-scan ultrasound of liver were recorded before and after the treatment for statistical analysis. Result After 6-month treatment, the body weight, BMI, abdomen circumference, hip circumference, arm circumference, and thigh circumference were significantly improved in the two groups (P<0.05); some patients had their TC, TG, AST and ALT levels descended to the normal range and B-scan ultrasound of liver turned negative; the reduction of abdomen circumference in the treatment group was more significant than that in the control group (P<0.05). Conclusion Cupping plus Chinese medication, diet control and exercises can effectively improve clinical observation indexes of NAFLD, especially for those with central obesity.