目的 探讨不同病程2型糖尿病患者冠脉血流速度储备(CFVR)功能的变化.方法 我院59例门诊就诊患者分为3组:糖耐量正常组23例,新诊断2型糖尿病患者组21例,已诊断2型糖尿病患者组15例.对3组对象应用腺苷诱导的超声心动图检查,探测左前降支血流速度的改变,评估各组间CFVR功能的改变.结果 糖耐量正常组、新发糖尿病患者组与已诊断糖尿病患者组CFVR功能逐渐下降,P＜0.01.结论 糖尿病患者CFVR功能显著降低,在新诊断的糖尿病患者内皮功能就已受损,而且随着糖尿病病程的延长进一步恶化.%Objective To investigate the change of coronary flow velocity reserve (CFVR) in patients with type 2 diabetes mellites for different course. Methods The 59 participants were divided into 3 groups: 23 normal glucose tolerance volunteers (group A) , diabetic patients including21 newly diagnosed (group B) and 15 already diagnosed from outpatient department (group C). The CFVR was assessed by using adenosine echocardiography. Result There was a gradual decline for CFVR among the group A, B and C (P <0.01). Conclusions Coronary artery endothelial function was impaired in diabetic patients, which was induced even in newly diagnosed diabetic patients and deteriorated with diabetic course.
展开▼
