首页> 外国专利> Compound, pharmaceutical composition, methods for treating or preventing cardiovascular disease, dyslipidemia, dyslipoproteinemia, glucose metabolism disorder, thrombotic and associated with peroxisome proliferator activated receptor, alzheimer's disease, x syndrome or metabolic syndrome , septicemia, obesity, pancreatitis, hypertension, kidney disease, cancer, inflammation and impotence, in a patient and to reduce the fat content of poultry eggs and poultry meat

Compound, pharmaceutical composition, methods for treating or preventing cardiovascular disease, dyslipidemia, dyslipoproteinemia, glucose metabolism disorder, thrombotic and associated with peroxisome proliferator activated receptor, alzheimer's disease, x syndrome or metabolic syndrome , septicemia, obesity, pancreatitis, hypertension, kidney disease, cancer, inflammation and impotence, in a patient and to reduce the fat content of poultry eggs and poultry meat

机译:化合物,药物组合物,用于治疗或预防心血管疾病,血脂异常,血脂异常,葡萄糖代谢异常,血栓形成以及与过氧化物酶体增殖物激活受体相关的药物,阿尔茨海默氏病,x综合征或代谢综合征,败血病,肥胖症,胰腺炎,高血压,肾脏疾病,癌症,炎症和阳ot,降低患者禽蛋和禽肉的脂肪含量

摘要

"COMPOSITION, PHARMACEUTICAL COMPOSITION, METHODS FOR TREATING OR PREDICTING CARDIOVASCULAR DISEASE, DYSLIPIDEMIA, DYSLIPOPROTEINEMIA, A DISEASE OF THE GLYDOS METABOLISM, RECEIVED WITH THE AXIS OF THE AEROSIS OF THE AXIS, DYNAMICS OF THE CARE METABOLICS, SEPTICEMIA, OBESITY, PANCREATITIS, HYPERTENSION, KIDNEY DISEASE, CANCER, INFLAMMATION AND IMPOTENCE, IN A PATIENT AND TO REDUCE THE FAT CONTENT OF BREEDING AND DUCKING DUCK. The present invention relates to novel sulfoxide and bisulfoxide compounds, compositions comprising sulfoxide and bisulfoxide compounds, and methods useful for treating and preventing cardiovascular disease, dyslipidemia, dysproteinemia, and glucose metabolism disorders comprising administering a composition comprising an ether compound. The compounds, compositions and methods of the invention are also useful for treating and preventing Alzheimer's disease, Syndrome X, peroxisome proliferator activated receptor related disorders, septicemia, thrombotic disorders, obesity, pancreatitis, hypertension, kidney disease, cancer. , inflammation and impotence. In certain embodiments, the compounds, compositions and methods of the invention are useful in combination therapy with other therapeutic products such as hypocholesterolemic and hypoglycemic agents.
机译:“组成,药物成分,治疗或预防心血管疾病,血脂异常,血脂蛋白异常,糖代谢紊乱的方法,包括轴索浮肿,桥骨折返,旋律,旋律,桥骨折断,旋转,折返患者和减少家禽和鸭鸭脂肪含量的肾脏疾病,癌症,炎症和阳IMP。本发明涉及新型亚砜和亚砜化合物,包含亚砜和亚砜化合物的组合物以及可用于治疗和预防心血管疾病的方法疾病,血脂异常,血脂异常和葡萄糖代谢失调,包括给予包含醚化合物的组合物。本发明的化合物,组合物和方法还可用于治疗和预防阿尔茨海默氏病,X综合征,过氧化物酶体增殖物激活的受体相关疾病,败血病,血栓形成障碍肥胖,胰腺炎,高血压,肾脏疾病,癌症。 ,发炎和阳ot。在某些实施方案中,本发明的化合物,组合物和方法可用于与其他治疗产品例如降胆固醇药和降血糖药的联合治疗。

著录项

  • 公开/公告号BR0114623A

    专利类型

  • 公开/公告日2005-12-13

    原文格式PDF

  • 申请/专利权人 ESPERION THERAPEUTICS INC.;

    申请/专利号BR20010114623

  • 申请日2001-10-11

  • 分类号C07C317/18;C07C317/10;C07C317/22;C07C317/44;C07D233/40;C07D233/42;C07D249/02;C07D257/04;C07D261/12;C07D305/12;C07D307/32;C07D309/12;C07D309/30;C07D309/40;C07D333/48;C07D335/02;C07D495/04;C07F9/09;C07F9/24;7A61KB;

  • 国家 BR

  • 入库时间 2022-08-21 21:40:23

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