目的：探讨哮喘患者抑郁状态发病率及其相关性。方法：选择我院门诊及住院哮喘患者128例，根据抑郁状态评定，通过SDS问卷调查，将纳入患者分为哮喘并发抑郁组（60例），单纯哮喘组（68例），对两组患者肺功能进行检测，并对哮喘控制测试表（ACT）评分进行统计分析。结果：哮喘并发抑郁的检出率为46．9％，哮喘并发抑郁组及单纯哮喘组之间，肺功能检测及ACT评分存在显著性差异（P＜0．05）；支气管哮喘并发抑郁组患者ACT评分值明显低于支气管哮喘组（P＜0．05），且ACT评分值与抑郁得分呈负相关（r＝－0．485，P＝0．000），肺功能检测与抑郁得分呈负相关（r＝－0．543P＝0．000）。结论：支气管哮喘并发抑郁的检出率较高，存在抑郁状态的哮喘患者肺功能差，病情控制不理想，抑郁等精神因素在哮喘的发生、发展及治疗过程中有着不可忽视影响。%Objective:To investigate the incidence of depression in patients with asthma and their correla‐tion .Methods:A total of 128 outpatient and inpatient with asthma were followed up and data on the score of ACT and pulmonary function testing were collected and analyzed .All the patients were divided into two groups according to the ZUNG Self‐rating depression scale(SDS) ,group1 :group with asthma with depression group is 60 cases ;group2 :group with asthma without depression group was 64 cases .Results:the detection rate of depressive in pa‐tients with asthma was 46 .9% ,asthma with depression group and asthma group ,lung function (FEV 1 .0 ,FVC , FEV 1 .0/FVC ,PEF) and ACT score exists significant differences ,the two groups was statistically significant (P<0 .05) .asthma with depression group ACT scores lower than asthma group (P <0 .05) ,and ACT scores and de‐pression scores were negatively correlated (r= -0 .485 P=0 .000) ,pulmonary function (FEV 1 .0/FVC) and de‐pression scores were negatively correlated (r= -0 .543 P=0 .000) .Conclusion:The prevalence of depression in pa‐tients with asthma is high ,and its level of control is worse than a simple asthma's ,depression and other psycholog‐ical factors would have a negligible impact in the occurrence ,development ,transfer process of asthma .
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