三七叶苷软胶囊改善睡眠功能试验研究

摘要

目的 研究三七叶苷软胶囊改善动物睡眠功能.方法 通过戊巴比妥钠睡眠时间实验、戊巴比妥钠阈下剂量催眠试验、巴比妥钠睡眠潜伏期实验对三七叶苷软胶囊进行检测.结果 能延长戊巴比妥钠睡眠时间、协同戊巴比妥钠阈下剂量催眠作用、缩短巴比妥钠睡眠潜伏期,与阴性对照组的差异具有显著性(P＜0.01或P＜0.05),无直接睡眠作用,对小鼠的体重无影响.结论 三七叶苷软胶囊具有改善睡眠功能作用.%Objective Research on Sanqi leaf glucoside soft capsule improving animals sleep. Methods Sanqi leaf glucoside soft capsule were detected through the sodium pentobarbital sleep time experiment, the nembutal subthreshold-hypnosis dose hypnotic experiment and the pentobarbital sodium sleep latency period experiment. Results The results showed that the sodium pentobarbital sleep time was lengthened, the nembutal subthreshold-hypnosis dose hypnotic effect was collaborated and the pentobarbital sodium sleep latency was shortened. Sanqi leaf glucoside soft capsule showed the significant difference with the negative control on improving animals sleep (P < 0.01 or P < 0.05). At the same time, Sanqi leaf glucoside soft capsule had no obvious effect on body weight in mice. Conclusion Sanqi leaves glucoside soft capsule improved sleep.