Aiming at Chinese Train Control System Level 3 and combining with layout of equipment of similar foreign systems, this paper proposes an integrated scheme to optimize the two systems of station interlocking and train control center. According to the design principles of the integrated system, the integrated model of dual host computers is established, in which, the logic host computer is in charge of all other functions except responder message and temporary speed restriction. On this basis, the external interface of the system and information exchange content and flow direction are analyzed, and the safety protection strategies of the integrated system are addressed in perspective of route release mechanism, information acquisition, information transfer and coding logic. The results show that the train control system protection can be improved by means of station-section integration and the structure with dual host computers is effective and feasible.%针对CTCS-3级中国列车运行控制系统，结合国外类似系统的设备配置状况，提出对车站联锁与列控中心两系统进行整合优化的一体化设计方案。依据一体化系统的设计原则，构建双主机结构的一体化模型，其中逻辑主机负责除应答器报文和临时限速处理功能外的所有功能。在此基础上，分析系统的外部接口以及信息交互内容和流向，并从进路解锁机制、信息采集、信息传递、发码逻辑等方面，阐述一体化系统的安全防护策略。研究表明：车站区间一体化的列车控制系统可实现更为完善的安全防护，双主机结构是有效可行的实现方案。
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