正常胰腺在3.0T MR不同DWI序列上的ADC值评价

摘要

Objective:To investigate ADC value of normal pancreas among different DWI sequences on a 3. OT MR scanner. Methods: Different DWI sequences were performed in 30 normal volunteers, based on SE EPI sequence and b values = 0 and 600s/mm2. DWI sequences included breath hold DWI with MPG pulses in X,Y,Z directions (BH600ALL) ,breath hold DWI with MPG pulses in Z direction (BH600SI) , respiratory triggered DWI with MPG pulses in X,Y,Z directions (TRIG600ALL) ,respiratory triggered DWI with MPG pulses in X,Y,Z directions and inversion recovery for fat saturation (TRIG600ALL+BS) and free breathing DWI with MPG pulses in X,Y,Z directions and inversion recovery for fat satura tion (FB600ALL+BS). ADC value of normal pancreas and different parts of pancreas were statistically investigated and compared among different DWI sequences by one way ANOVA and LSD test through the software SPSS16. 0. Results, ADC value of normal pancreas showed noticeably statistical difference among BH600ALL, BH600SI, TRIG600ALL, TRIG600ALL+BS and FB600ALL + BS DWI sequences (P<0. 001) : Among those five different DWI sequences, FB600ALL+BS had the highest ADC value,while BH600SI had the lowest ADC value. ADC value of the head,body and tail of pancreas showed statistical difference in each DWI sequence (P<0. 05) : ADC value in the head of pancreas was the lowest compared to that in the body and tail of pancreas and the statistical difference in ADC value was noticed between the head and tail of pancreas on each DWI sequence (P-<0. 05). Conclusion: ADC value of normal pancreas is different among different DWI sequences and heterogeneous among different parts of pancreas at a 3. 0T MR scanner.%目的:分析评价正常胰腺在3.0T MR不同DWI序列上的表观扩散系数(ADC)值.方法:在3.0T MR上,对30例正常志愿者行基于自旋回波平面回波(SE-EPI)序列的不同DWI扫描(b值为0和600 s/mm2),包括X、Y、Z三轴扩散梯度憋气DWI(BH600ALL)、Z轴扩散梯度憋气DWI(BH600SI)、呼吸门控DWI(TRIG600ALL)、呼吸门控反转恢复脂肪抑制DWI(TRIG600ALL+BS)及自由呼吸反转恢复脂肪抑制DWI(FB600ALL+BS),应用SPSSl6.0统计学软件,采用单因素方差分析和LSD检验比较分析不同DWI序列中正常胰腺及胰腺不同部位的ADC值.结果:正常胰腺在BH600ALL、BH600SI、TRIG600 ALL、TRIG600ALL+BS和FB600ALL+BS 5个DWI序列中的ADC值差异具有统计学意义(F=21.864,P<0.001),胰腺ADC值在FB600ALL+BS序列上最高,BH600SI序列上最低;各序列胰腺不同部位的ADC值差异具有统计学意义(P均<0.05),胰头的ADC值最低,且与胰尾的ADC值差异具有统计学意义(P均<0.05).结论:正常胰腺在3.0T MR不同DWI序列的ADC值不同,且在胰腺不同部位呈现不均衡表现.