目的:探讨肝脏假性淋巴瘤的临床病理特征、免疫表型及鉴别诊断.方法:在光学显微镜下对肝脏假性淋巴瘤进行组织学形态观察,并借助免疫组化进一步对其形态进行分析.由于原发于肝脏的假性淋巴瘤极为罕见,故本文将报道一例发生于肝脏的假性淋巴瘤,结合文献探讨其临床病理特点,以提高诊断及鉴别诊断水平.结果:大体上为切面可见灰白结节,结节切面灰白色,质地中等,与周围分界清,周围肝组织灰红质软.显微镜下组织学表现为肝周边淋巴结淋巴组织增生,细胞大小较一致,核圆形,细胞无异型,未见明显核分裂,其中见嗜酸性白细胞浸润及少数异型细胞.免疫组化显示肿瘤细胞表达CD3、CD20及CD30.结论:肝脏假性淋巴瘤为罕见的、良性淋巴组织增生性病变,形态学特征、免疫组化染色在肝假性淋巴瘤诊断中具有重要价值.在临床病理实践中,必须首先与常见的发生于该部位恶性肿瘤如霍奇金淋巴瘤肿瘤等鉴别.%Objective:To explore the clinical pathological characteristics of liver pseudo lymphoma,immune phenotype and differential diagnosis.Methods:Under optical microscope to histological morphology of liver pseudo lymphoma,and with the aid of immunohistochemical further analysis of its shape.Due to primary pseudo lymphoma is rare in the liver,so this article will report a pseudo lymphoma occurring in the liver,as well as to explore the clinical and pathological characteristics to improve the levels of differential diagnosis.Results:In general for the section visible gray nodules,nodal plane hoar,quality of a material medium,with the surrounding boundaries clear,red soft liver tissue around the ashes.Microscope histological characterized by hepatic peripheral lymphoid tissue lymph node hyperplasia,cell size is consistent,circular,nuclear cells without atypia,did not see obvious nuclear fission,see the eosinophilic leukocyte infiltration and a few different cells.Immunohistochemistry showed that tumor cells expressed CD3,CD20 and CD30.Conclusion:Pseudo liver lymphoma is a rare,benign lymphoid tissue proliferative lesions,morphology,immunohistochemical staining is of important value in the diagnosis of liver pseudo lymphoma.In clinical practice,must first occurred in the region of common malignant tumor with identification such as Hodgkin's lymphoma tumor.
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