四磨汤口服液联合金双岐治疗小儿功能性消化不良疗效观察

摘要

目的：观察四磨汤口服液联合金双岐治疗小儿功能性消化不良的临床效果、安全性及停药后的复发率。方法：将92例临床诊断为功能性消化不良的小儿分为治疗组（52例）和对照组（40例），治疗组采用四磨汤口服液联合金双岐，口服2周，对照组给予胃蛋白酶颗粒口服2周，疗程结束后比较两组患儿的临床疗效，观察用药期间的不良反应，结束治疗1个月后统计两组患儿的复发率。结果：治疗组疗程结束后食欲改善、食量增加明显好于对照组，有效率78.8％，对照组有效率57.5％，两组比较差异有统计学意义（P ﹤0.05）；两组患儿治疗期间均未见明显不良反应，结束治疗1个月后治疗组复发8例，复发率19.5％，对照组复发11例，复发率47.8％，，两组比较差异有统计学意义（P ﹤0.05）。结论：四磨汤口服液联合金双岐治疗小儿功能性消化不良显效快、疗效好、安全、无不良反应、复发率低。%Objective:To observe the clinical effect of Simotang oral liquid combined with Jinshuangqi,treatment of chil-dren with functional dyspepsia observe the effect of Simo decoction combined with clinical effect,safety of Jinshuangqi in trea-ting children with functional dyspepsia and the relapse rate after stopping. Methods:The clinical diagnosis for 92 cases of func-tional dyspepsia in children divided into treatment group of 52 cases,with Simotang oral liquid combined with Jinshuangqi oral-ly for 2 weeks,the control group of 40 patients with pepsin granules orally for 2 weeks,the clinical efficacy of the two groups of children before and after treatment,adverse effects were observed during the treatment,1 months after the end of treatment of two groups of children with recurrent rate statistics. Results:The end of the treatment group after treatment improved appetite, food intake increased significantly better than the control group,the effective rate of treatment group 78. 8% ,the control group was 57. 5% ,the total effective rate of treatment group was higher than that of the control group,there was significant difference between two groups(P ﹤ 0. 05),during the two groups were no obvious adverse reaction of treatment,The end of 1 months after treatment the treatment group of 8 cases of recurrence,the recurrence rate is 19. 5% ,the control group of 11 cases of recur-rence,the recurrence rate is 47. 8% ,there was significant difference between two groups(P ﹤ 0. 05). Conclusion:Simotang o-ral liquid combined with Jinshuangqi in treating children with functional dyspepsia fast effect,good curative effect,safety,no toxic side effect,the low recurrence rate of symptoms improved.