间歇与持续经鼻气道正压通气治疗极低和超低出生体重早产儿反复呼吸暂停的疗效比较

摘要

目的：观察经鼻间歇正压通气（ NIPPV）与经鼻持续气道正压通气（ NCPAP）治疗极低和超低出生体重早产儿原发性呼吸暂停的疗效。方法2013年6月至2015年6月在我院诊断为反复呼吸暂停的极低和超低出生体重早产儿72例，分为NIPPV组38例及NCPAP组34例分别在常规综合治疗的基础上给予NIPPV、NCPAP治疗，观察并比较两组的疗效。结果两组治疗后1 h及12 h血气分析比较差异有统计学意义（P＜0.05）。 NIPPV组治愈率及有效率均优于NCPAP组，差异有统计学意义（ P＜0.05）。结论与NCPAP相比，NIPPV治疗极低和超低出生体重早产儿原发性呼吸暂停疗效显著。%Objective To observe the curative effect of nasal intermittent positive pressure ventilation( NIPPV) and nasal con-tinuous positive pressure ventilation( NCPAP) in the treatment of recurrent apnea in premature infants with very low birth weight or ex-tremely low birth weight.Methods From June,2013 to June 2015,72 premature infants with very low birth weight or extremely low birth weight who were diagnosed as recurrent apnea were randomly given NIPPV or NCPAP therapy on the basis of the comprehensive treatment,respectively.The curative effect was compared between the two groups.Results The differences in blood gas analysis after 1 h and 12 h of the treatment were statistically significant between the two groups(P<0.05).The cure rate and effective rate in the NIP-PV group were better than that in the NCPAP group(P<0.05).Conclusion The effects of NIPPV were more significant than that of NCPAP in the treatment of recurrent apnea in premature infants with very low birth weight or extremely low birth weight.