间甲酚催化烷基化合成2，3，6-三甲基苯酚

摘要

2，3，6-trimethylphenol which is useful as intermediates for vitamin E and pesticides was prepared by vapor-phase methylation of m-cresol with methanol in a fixedbed tube reactor in the presence of a metal oxide catalyst.The influence of temperature，space-velocity and feed molar ratio on the yield of 2，3，6-trimethylphenol was examined.The synthesis process was also described in detail.The results show that the catalysts have higher reactivity and selectivity.The conversion of m-cresol is 99.89％，the selectivity of 2，3，6-trimethylphenol is 90.80％.%采用自行研制开发的新型铁系复合氧化物催化剂，以间甲酚为原料，甲醇作甲基化剂，在固定床管式反应器中进行催化反应，一步合成2，3，6-三甲基苯酚，考察了温度、空速及原料配比对反应的影响。结果表明，在LHSV 0．8 h-1、反应压力 0．2 MPa、温度 360 ℃、间甲酚／甲醇／水摩尔比为1／6／2的条件下，间甲酚的单程转化率为99.89％；2，3，6-三甲基苯酚选择性为90.80％。