探讨三种血清学检测方法在梅毒诊断中的应用

摘要

Syphilis serological detection is the major diagnosis of syphilis,and is of great significance to decrease the spread of syphilis and monitor the therapeutic efficacy. Here is to summarize three syphilis serological detection methods,toluidine red unheated serum test( TRUST ), enzyme-linked immunosorbent assay ( EL1SA ),and treponema pallidum particle assay( TPPA ),to find the optimal application plan. Currently, EL1SA-TPPA-TKUST combination is the best way and the most common method to diagnose syphilis.%梅毒血清学检测方法是诊断梅毒的主要方法,对于控制梅毒的蔓延和监测疗效具有重要意义.在此就三种血清学检测方法,即甲苯胺红不加热血清反应素试验(TRUST)、酶联免疫吸附试验(ELISA)和梅毒螺旋体明胶颗粒凝集试验(TPPA)在梅毒诊断过程中的应用进行综述,并探讨其最佳的应用方案.就目前阶段而言,ELISA-TPPA-TRUST联合应用是最佳的应用方案,在临床诊断梅毒中最常用.