舒利迭对小儿支气管哮喘患者红细胞免疫、外周血T淋巴细胞亚群及免疫球蛋白水平影响的研究

摘要

Objective To study the influence of seretide on the erythrocyte immune,peripheral blood T lymphocyte subsets and immunoglobulin of pediatric patients with bronchial asthma.Methods Seventy-four pediatric patients with bronchial asthma in TCM Hospital of Xianning City from August 2008 to January 2012 were selected as research objects,and they were randomly divided into control group and observation group with 37 cases in each group,the control group were treated with routine treatment,and the observation group were treated with seretide based on the treatment of control group,then the erythrocyte immune,peripheral blood T lymphocyte subsets and immunoglobulin of two groups before and one week,two weeks after the treatment were detected and compared.Results The improvement ranges of erythrocyte immune,peripheral blood T lymphocyte subsets and immunoglobulin of the observation group one week and two weeks after the treatment were all bigger than those of the control group,and those items of observation group two weeks after the treatment were all better than those one week after the treatment (all P ＜ 0.05).Condusion The influence of seretide for the erythrocyte immune,peripheral blood T lymphocyte subsets and immunoglobulin of pediatric patients with bronchial asthma is obvious,and it plays an active role in improving the comprehensive immune state of pediatric patients.%目的 探讨舒利迭(沙美特罗替卡松粉吸入剂)对小儿支气管哮喘患者红细胞免疫、外周血T淋巴细胞亚群及免疫球蛋白水平的影响.方法 将咸宁市中医院于2008年8月至2012年1月收治的74例小儿支气管哮喘患者随机分为对照组和观察组,各37例,对照组进行常规治疗,观察组在对照组治疗的基础上加用舒利迭治疗,然后将两组患者治疗前及治疗后l周、2周的红细胞免疫、外周血T淋巴细胞亚群及免疫球蛋白水平进行检测并进行比较.结果 观察组治疗后1周及2周的红细胞免疫、外周血T淋巴细胞亚群及免疫球蛋白水平改善幅度均大于对照组,且观察组治疗后2周优于治疗后1周(均P＜0.05).结论 舒利迭对小儿支气管哮喘患者红细胞免疫、外周血T淋巴细胞亚群及免疫球蛋白水平影响较为明显,对于改善患儿的整体免疫状态有积极的作用.