目的 探讨新型环路内直接加热式七氟醚蒸发器低新鲜氧流量吸入诱导临床应用价值.方法 将60例接受全麻乳腺手术的女性患者随机分为环路内组(In G)与环路外组(Out G),In G采用新型环路内直接加热式七氟醚蒸发器低新鲜氧流量吸入诱导,Out G采用传统环路外自动温度补偿式七氟醚蒸发器高新鲜氧流量吸入诱导,两组均采用潮气量法完成吸入诱导,观察患者在意识消失时间、七氟醚消耗量、不良反应及吸入诱导再接受度的区别,并分别对环路内七氟醚出现时间与其诱导时间相关分析.结果 ①两组间诱导前后生命体征变化及不良反应无明显差异.②In G 比Out G意识消失快9.5 s(t=-2.302,P=0.026),诱导中In G比Out G少消耗液态七氟醚0.7 ml(t=-3.819,P=0.000).③两组间患者再接受吸入诱导程度无明显差异(χ2=0.289,P=0.591).结论 新型环路内直接加热式七氟醚蒸发器低新鲜氧流量吸入诱导优于传统环路外自动温度补偿式七氟醚蒸发器高新鲜氧流量吸入诱导.%Objective To investigate the clinical value of the newly in-circuit direct heating vaporizer in low O2 fresh flow in inhalation induction with sevoflurane. Methods 60 cases of female patients with breast surgery by general anesthesia were randomly divided into in-circuit group (In G) and out-circuit group ( Out G). In G were treated with the newly in-circuit direct heating vaporizer in low O2 fresh flow to complete inhalation induction with sevoflurane. Out G were treated with the traditional out-circuit automatic temperature compensating vaporizer in high O2 fresh flow to complete inhalation induction with sevoflurane. Both groups were inducted by tide volume method. The time of consciousness loss, sevoflurane consumption, adverse reactions, acceptance of inhalation induction, and correlation analysis between the time of sevoflurane appearance in the circuit and time of induction were analyzed. Results There were no difference in vital signs changes in the induction and adverse reactions. Patients of In G's consciousness loss time was 9. 5s faster than Out G's (t= -2. 302,P=0. 026), and patients of In G' s consumption of liquid sevoflurane was 0. 7ml less than Out G's (t=-3. 819,P=0. 000). The acceptance of inhalation induction was same between the groups (x2 =0. 289,P=0 . 591). Conclusion The newly in-circuit direct heating vaporizer is better than the traditional out-circuit automatic temperature compensating vaporizer in high O2 fresh flow inhalation induction with sevoflurane.
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