初诊2型糖尿病患者甲状腺结节影响因素分析

摘要

Objective To observe influence factors between Thyroid Nodules (TN) and clinical characteristics in the newly-diagnosed Type 2 Diabetes Mellitus patients.Methods 239 patients with the newly-diagnosed T2DM were selected in department of Endocrinology, Beijing Chuiyangliu Hospital.According to ultrasound of thyroid, these patients were divided into two groups:the group with TN (n=79) and the group without TN (n=160).Clinical characteristics and thyroid function were compared in these groups.Results The overall prevalence of TN was 33.1% in the newly-diagnosed T2DM patients.The prevalence of TN in females was 44.1%, higher than that in males, which was 26.0%.There were differences in age and serum 25(OH) vitamin D in these groups (P<0.05).The Logistic regression analysis showed that female, age, smoke, TgAb were positive correlated with TN (P<0.05).Conclusion Female, age, smoke, TgAb are important risk factors for Thyroid Nodules in the newly-diagnosed T2DM patients.%目的 探讨影响初诊2型糖尿病(T2DM)患者甲状腺结节的危险因素.方法 选择北京市垂杨柳医院内分泌科2015年5月至2016年10月的初诊2型糖尿病患者239例.根据甲状腺彩超结果分为有结节组(n=79)和无结节组(n=160),进行初诊2型糖尿病患者甲状腺结节与临床指标、甲状腺功能的相关性分析.结果 初诊2型糖尿病患者甲状腺结节的患病率33.1%;女性患病率44.1%,明显高于男性患病率26.0%.两组间的年龄、血清25羟维生素D[25(OH)D]比较差异有统计学意义(P<0.05).Logistic回归分析结果显示女性、年龄、吸烟、甲状腺球蛋白抗体(TgAb)与甲状腺结节呈独立正相关(P<0.05).结论 女性、年龄、吸烟、TgAb是初诊2型糖尿病患者甲状腺结节的独立危险因素.