目的:评价生物补片应用于腹腔镜抗反流手术治疗胃食管反流病的效果。方法:回顾2012年12月至2014年4月在浙江大学医学院附属邵逸夫医院普外科收治的20例有典型临床症状的胃食管反流病患者,接受腹腔镜食管裂孔修补加360°胃底折叠术,使用4层猪小肠黏膜下层基质补片进行食管裂孔加强修补。结果:20例患者的腹腔镜手术均成功,未发生术中并发症。术后症状均消失,随访3~18个月未复发,有6例患者出现吞咽困难,其中5例经保守治疗好转,1例接受食管下端扩张术。结论:腹腔镜抗反流手术治疗胃食管反流病时,使用4层猪小肠黏膜下层基质补片进行食管裂孔加强修补的效果令人满意。%Objective:To evaluate the application of biological mesh in laparoscopic anti-reflux procedure for gastroesophageal reflux disease ( GERD ).Methods: The clinical data of 20 consecutive GERD patients underwent anti-reflux surgery in Sir Run Run Shaw Hospital from December 2012 to April 2014 were retrospectively analyzed . The laparoscopic hiatal repair with 360 fundoplicaiton was performed and the biological mesh ( Biodesign TM , Surgsis ® ) was implanted for reinforcement of hiatal repair . Results: All laparoscopic procedures were successful , no conversion and no intra-operative complications occurred .The pre-operative complains were relieved in all patients, and no recurrence was observed during 3-18 month of follow-up.Six patients got dysphagia after operation; 5 of them were controlled through medication and psychological induction;1 received esophageal dilatation by bougie .Conclusion: The application of biological mesh in laparoscopic anti-reflux procedure for gastroesophageal reflux disease is satisfactory .
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