目的 探讨髓芯减压联合干细胞移植治疗早期股骨头坏死的临床疗效.方法 对18例早期股骨头坏死患者行髓芯减压联合干细胞移植治疗,并观察临床疗效.结果 18例患者均顺利完成手术,平均手术时间(35.4±5.2) min;术后平均住院(8.5±1.2)d.术前Harris评分50.2±3.3,术后Harris评分为85.6±4.2,术后Harris评分显著高于术前(P＜0.05).术前股骨头坏死中心区MRI影像低信号区所占比例为(26.2±6.3)％,术后为(11.3±4.3)％,术后股骨头坏死中心1 a MRI影像低信号区较术前明显减少(P＜0.05).结论 髓芯减压联合干细胞移植治疗早期股骨头坏死疗效确切.%Objective To study the clinical effect of core decompression combined with stem cells transplantation for treatment of early femoral head necrosis. Methods Eighteen patients with early femoral head necrosis were treated with core decompression and stem cells transplantation, and the clinical effect was observed. Results The operations were successful in eighteen patients,the average operation time was (35.4±5.2) minutes,and the average hospital stay was (8.5 ±1.2) days. The Harris scores was 50. 2 ±3. 3 and 85. 6 ±4. 2 before and after treatment,the score after treatment was significantly higher than that before treatment ( P < 0. 05) . The ratio of low signal area of the central area of necrosis in MR] images was (26.2 ± 6.3)% and (11.3 ±4.3)% before and after treatment,the ratio after treatment was significantly lower than that before treat-ment(P<0. 05). Conclusion Core decompression combined with stem cell transplantation is an effective treatment for early femoral head necrosis.
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