为阐明溪黄草[Isodon serra(Maxim.)Kudo]地上部分的化学成分,采用色谱分离方法从其乙醇提取物中得到9个化合物.经光谱数据对比,它们的结构分别鉴定为迷迭香酸甲酯 (1)、3,3′-双(3,4-二氢-4-羟基-6,8-二甲氧基-2H-1-苯并吡喃) (2)、7-大柱香波龙烯-3,5,6,9-四醇 (3)、7-大柱香波龙烯-3,5,6,9-四醇9-O-β-D-葡萄糖苷 (4)、5,6-环氧-7-大柱香波龙烯-3,9-二醇 (5)、(?)-黑麦草内酯 (6)、3-醛基吲哚 (7)、乙基α-L-呋喃阿拉伯糖苷 (8)和乙基β-D-木糖苷 (9).化合物1和2为苯丙素类、3~6为大柱香波龙烷类、7为生物碱类、8和9为烷基糖苷类.化合物2~9为首次从该植物中报道.%To clarify the chemical constituents in the aerial parts of Isodon serra(Maxim.)Kudo,nine compounds were isolated from the ethanol extract. Basis on the spectral data, their structures were identified as methyl rosmarinate (1), 3,3′-bis(3,4-dihydro-4-hydroxy-6,8-dimethoxy-2H-1-benzopyran) (2), 7-megastigmene-3,5,6,9-tetrol (3), 7-megastigmene-3,5,6,9-tetrol 9-O-β-D-glucopyranoside (4), 5,6-epoxy-7-megastigmene-3,9-diol (5), (?)-loliolide (6), 3-formylindole (7), ethyl α-L-arabinofuranoside (8), and ethyl β-D-xylopyranoside (9). Compounds 1 and 2 belong to phenylpropanoids, 3–6 are megastigmanes, 7 is an alkaloid, 8 and 9 are alkyl glycosides. Compounds 2–9 were reported from this species for the first time.
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