不同溶剂对聚吡咯/涤纶材料抗凝血性能的影响

摘要

为改善涤纶材料的抗凝血性能,在涤纶织物表面涂覆具有良好生物相容性的聚吡咯.采用原位聚合的方法,利用不同的溶剂获得具有不同表面性能的聚吡咯涂层,通过动态凝血性能测试表征复合材料的抗凝血性能.结果表明:在不同溶剂和不同比例的混合溶剂中可得到具有不同表观形态和表观深度的聚吡咯涂层,在水溶液中得到的表观深度最小;腈水混合溶剂中,随着腈水比的增大,K/S值越大,在腈水比较小时所得聚吡咯复合织物的聚吡咯镀膜较光滑.抗凝血试验结果表明:十六烷基三甲基溴化铵与吡咯(CTAB/Py)量比为1:2条件下的抗凝血程度最好,5 min时所制得的试样抗凝血程度较未涂层的涤纶织物提高了140%;抗凝血程度与织物上聚吡咯的微观形态及表面性能有关.%In order to improve the cytocompatibility of polyester(PET)materials,polypyrrole(PPy)with good biocompatibility was coated on PET fabric. In situ polymerization using different solvents was used to prepared polypyrrole coating with different surface performances.The performance of dynamic blood clotting test was carried out to characterize anticoagulant properties of composited materials. The results show that different surface morphologies and K/S values can be acquired using different solvents and different ratios for the mixed solvents. The K/S value is smallest in the water as the solvent. For ACN/water solvent,with the increase of ACN/water ratio, the K/S value increases and the surface of PPy/PET is smoother when ACN/water ratio is smaller. BCI is the best when CTAB/Py is 1:2, improves about 140% at 5 min compared to the uncoated PET fabrics. Anticoagulant properties are related to micromorphology and surface properties of PPy.