目的:通过分析我院鼻咽癌患者情况,了解本院鼻咽癌疗效及预后影响因素.方法:收集1996年4月1日至2007年3月1日期间住院治疗的238例初治鼻咽癌患者资料,Kaplan-Meier法进行生存分析.Log-Rank法检验生存率之间的差异.Cox回归模型进行多因素分析.结果:1、3、5、8、10年的总生存率分别为95.6％、85.2％、76.6％、63.2％和58.3％.单因素分析显示年龄、T分期、N分期和总分期是影响鼻咽癌患者预后的危险因素.Cox多因素分析显示年龄、T分期、N分期是独立预后危险因素.结论:我院鼻咽癌治疗水平与文献报告相当.重视治疗过程中的年龄因素和分期因素,早诊早治可能有助于提高鼻咽癌疗效.%Objective To evaluate the survival rates and prognostic factors of patients with nasopharyngeal carcinoma. Methods 238 patients with nasopharyngeal carcinoma from April 1996 to March 2007 were enrolled in this study. Kaplan-Meier, Log-Rank, and Cox regression model were employed to analyze the survival rates, differences, and the prognostic factors, respectively. Results The 1, 3, 5, 8, and 10 years overall survival rates were 95.6%, 85.2%, 76.6%, 63.2%, and 58.3%, respectively. Age, T stage, N stage, and clinical stage were -the prognostic factors identified by survival analysis. Cox analysis confirmed that age, T stage, and N stage were the independent prognostic factors. Conclusions Take the prognostic factors seriously may improve the survival rates in patients nasopharyngeal carcinoma.
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