Objective To fully understand the handicaps for evidence-based practice and its influencing factors and to provide evidence for intervention. Methods With Chinese version of Handicap Inventory Short Form about Evaluation of Evidence-Based Nursing Practice developed by LIU Xiao-hua, a cross-sectional survey was conducted among 831 clinical nurses in Zhejiang Province. Results Though with well knowledge of evidence-based practice in nursing, 70.7%of the nurses proposed there existed handicaps in evidence-based practice. Insufficient resources of implementing evidence-based practice and low quality of nursing search report scored higher. There were less handicaps among nurses after training of evidence-based practice in nursing, those with senior positions and those in department of nursing administration, emergency and ICU (P<0.05). Conclusion There are many handicaps for evidence-based practice in nursing. Great emphasis should be laid to scientific research of nursing. Sufficient evidence-based practice resources and various evidence-based practice in nursing education for nurses would contribute to the development of evidence-based nursing practice.% 目的全面了解浙江省临床护士的循证实践障碍现状，并分析其影响因素，为护理管理者实施干预提供可靠的参考依据.方法采用刘晓华等研制的中文版循证护理实践障碍量表，对浙江全省11个行政区22所医院共831名临床护士进行横断面调查.结果70.7%的临床护士认为自己循证实践存在障碍，但对循证护理的认识较好，得分较高的是开展循证护理的资源条件不足和护理研究报道的质量不高.参加过循证护理培训、职务较高和在护理部、急诊室、ICU等部门工作的护士循证实践障碍较小(P<0.05).结论浙江省临床护士循证实践障碍较严重，管理者应重视护理科研，营造良好的科研氛围；提供简单有效的循证资源，完善图书馆、数据库资源等硬件设施，提供坚实的物质基础；加强循证护理教育，提高不同层次临床护士的循证素质，缩小护理实证到临床应用的差距，促进循证护理的发展.
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