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应用CAT问卷评估AECOPD患者病情的临床研究

         

摘要

目的:探讨COPD患者自我评估测试(CAT)问卷应用于急性加重期COPD (AECO-PD)病情评估的临床价值。方法选择132例住院AECOPD患者,根据气流阻塞程度分为Ⅰ、Ⅱ、Ⅲ、Ⅳ级,入院后48 h内及出院后4周分别进行肺功能检测及CAT评分,并对结果作对比分析。结果Ⅰ~Ⅲ级AECOPD患者的CAT评分的变化与气流阻塞的改善有关(P均<0.05),而Ⅳ级患者的CAT评分变化与气流阻塞的变化无关(P>0.05)。Ⅳ级患者中,并发症≥3个的患者CAT评分低于并发症≤2个的患者[(26.9±4.3)vs.(31.8±5.1),P<0.05]。结论 CAT问卷评估Ⅰ~Ⅲ级AE-COPD的病情变化具有较好的敏感性,合并症≥3个的Ⅳ级患者的CAT评分高于合并症≤2个的患者。%Objective To explore the clinical value of the COPD assessment test (CAT)in evalua-ting the severity of acute exacerbations of chronic obstructive pulmonary disease (AECOPD). Methods A to-tal of 132 hospitalized patients with AECOPD were divided into four groups according to the degree of airflow obstruction. All patients underwent lung function test and CAT questionnaire within 48 h after hospitalization and 4 weeks after discharge. Results Except for the patients with gradeⅣAECOPD (P>0. 05 ),the changes in CAT scores of those with gradesⅠ,Ⅱ and Ⅲ were correlated with the improvement of airflow construction (all P<0. 05 ). For patients with grade ⅣAECOPD,the CAT scores in patients with≥3 types of complica-tions were significantly lower compared with those with ≤ 2 types of complications (26. 9 ±4. 3 vs. 31. 8 ± 5. 1,P<0. 05). Conclusions CAT questionnaire had a high sensitivity in assessing the changes in grades I~III AECOPD. In addition,patients with≥3 types of complications had significantly higher CAT scores com-pared with those with ≤2 types of complications.

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