超声引导下细针穿刺细胞学检查在甲状腺癌诊断中的应用

摘要

目的:评价超声引导下细针穿刺细胞学检查(FNAC) 在甲状腺癌诊断中的作用.方法:对比分析63例甲状腺结节细针穿刺后行手术治疗患者的细胞病理学与组织病理学诊断结果.结果:细针穿刺细胞学结果与术后组织病理学诊断结果比较,诊断总符合率为90.48% (57/63),kappa=0.883(P＜0.05)FNAC 判断甲状腺良恶性结节性质的敏感性、特异性和诊断准确率分别为78.95%、95.45%和90.48%.结论:FNAC对甲状腺癌诊断价值较高,与组织病理学检查总体诊断符合率较好,是一种安全、有效的术前确诊手段.%Objective: To investigate the diagnostic value of ultrasound guided fine needle aspiration cytology C FNAC ) for thyroid carcinoma. Methods : The cytological and histological results of 63 patients who had undergone FNAC for thyroid nodules, followed by thyroidectomy, were compared to evaluate the accuracy of cytological diagnosis of thyroid nodules. Results : The total diagnostic accordance rate of fine needle aspiration cytology was 90. 48％ ( 57/ 63 ) compared with that of histopathology, generating a kappa value of 0. 883( P ＜ 0. 05 ). In diagnosis of the benign and malignant thyroid nodules the sensitivity,specificity , and diagnostic accuracy of FNAC were 78. 95％ , 95. 45％ , and 90. 48％ . Conclusion: The diagnostic value of FNAC is high for thyroid carcinoma . Most of thyroid nodules have high total diagnostic accordance rate. FNAC is a safe and available method in the diagnosis of thyroid nodules preoperatively.